DKKL1 - dickkopf like acrosomal protein 1 Gene
Also Known as SGY; CT34; SGY1; SGY-1
Species: Homo sapiens
About DKKL1
This gene has 6 transcripts (splice variants) and 92 orthologues. Restricted expression toward testis (RPKM 49.6).
Summary
The dickkopf protein family interacts with the Wnt signaling pathway and its members are characterized by two conserved cysteine-rich domains. This gene encodes a secreted protein that has low sequence similarity to the dickkopf-3 protein. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
DKKL1 Products (3)
| mRNA | Protein | Name |
|---|---|---|
| NM_001197301.2 | NP_001184230.1 | dickkopf-like protein 1 isoform 2 precursor |
| NM_001197302.2 | NP_001184231.1 | dickkopf-like protein 1 isoform 3 |
| NM_014419.4 | NP_055234.1 | dickkopf-like protein 1 isoform 1 precursor |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
dickkopf-like protein 1 |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Rectum Adenocarcinoma |
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| Rectal Benign Neoplasm |
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| Trachea Carcinoma |
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| Rectum Cancer |
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| Male Infertility |
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Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Rattus norvegicus | DKKL1 | RGD | RGD:1563523 |
| Felis catus | DKKL1 | VGNC | VGNC:61507 |
| Canis familiaris | DKKL1 | VGNC | VGNC:39973 |
| Macaca mulatta | DKKL1 | VGNC | VGNC:109615 |
| Bos taurus | DKKL1 | VGNC | VGNC:28083 |
| Mus musculus | DKKL1 | MGD | MGI:1354963 |
| Others | DKKL1 | NCBI |