Phlda3 - pleckstrin homology like domain, family A, member 3 Gene

Also known as Tih1

About Phlda3

Summary

Predicted to enable phosphatidylinositol phosphate binding activity and phosphatidylinositol-3,4-bisphosphate binding activity. Predicted to be involved in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; negative regulation of protein kinase B signaling; and positive regulation of apoptotic process. Predicted to act upstream of or within apoptotic process. Predicted to be located in cytoplasm and membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including extraembryonic component; genitourinary system; hemolymphoid system; intestine; and liver. Orthologous to human PHLDA3 (pleckstrin homology like domain family A member 3). [provided by Alliance of Genome Resources, Apr 2022]