ZNF638 - zinc finger protein 638 Gene

Also Known as ZFML; NP220; Zfp638

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 27332

About ZNF638

Cytogenetic location: 2p13.2 Genomic coordinates (GRCh38): 2:71,331,782-71,435,061 (from NCBI)

This gene has 27 transcripts (splice variants), 174 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 14.1), thyroid (RPKM 11.9) and 25 other tissues.

Summary

The protein encoded by this gene is a nucleoplasmic protein. It binds cytidine-rich sequences in double-stranded DNA. This protein has three types of domains: MH1, MH2 (repeated three times) and MH3. It is associated with packaging, transferring, or processing transcripts. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]

ZNF638 Products (4)

mRNA Protein Name
NM_001014972.3 NP_001014972.1 zinc finger protein 638 isoform 1
NM_001252612.2 NP_001239541.1 zinc finger protein 638 isoform 1
NM_001252613.2 NP_001239542.1 zinc finger protein 638 isoform 2
NM_014497.5 NP_055312.2 zinc finger protein 638 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32814053 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZNF638 Protein Structure

(678 - 745)

  • 0
  • 400
  • 800
  • 1200
  • 1600
  • 1978 a.a.
Protein Preferred Names Protein Names

zinc finger protein 638

  • CTCL tumor antigen se33-1

Related Diseases

Diseases Alias
Lymphoma

  • Lymphoid Cancer

  • Lymphomas

  • Lymphoid Cancers

  • Lymphoid Neoplasm

  • Lymphoma Nos

  • Nhl - [Non-Hodgkin Lymphoma]

  • Non-Hodgkin Lymphoma

  • Non-Hodgkin Lymphoma, Nos

  • Non-Hodgkin Malignant Lymphoma Nos
Acromesomelic Dysplasia 2b

  • Fibular Hypoplasia And Complex Brachydactyly

  • Du Pan Syndrome

  • AMD2B

  • Dupans

  • Acromesomelic Dysplasia-2b

  • Fibular Aplasia-Complex Brachydactyly Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16161 ZNF638 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus ZNF638 MGD MGI:1203484
Bos taurus ZNF638 VGNC VGNC:37318
Felis catus ZNF638 VGNC VGNC:67340
Macaca mulatta ZNF638 VGNC VGNC:79098
Canis familiaris ZNF638 VGNC VGNC:48781
Rattus norvegicus ZNF638 RGD RGD:1309746
Others ZNF638 NCBI