Lsm2 - LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated Gene

Also Known as G7b; SmX5; Dmapl; Sm-X5; snRNP; Dmpkap; D17H6S56E2; D17H6S56E-2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 27756

Summary

Enables protein kinase binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to act upstream of or within mRNA catabolic process and spliceosomal tri-snRNP complex assembly. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be part of Lsm1-7-Pat1 complex; Lsm2-8 complex; and nucleus. Predicted to be active in P-body. Orthologous to human LSM2 (LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated). [provided by Alliance of Genome Resources, Apr 2022]

Lsm2 Products (4)

mRNA Protein Name
NM_001110101.2 NP_001103571.1 U6 snRNA-associated Sm-like protein LSm2 isoform 2
NM_001204273.1 NP_001191202.1 U6 snRNA-associated Sm-like protein LSm2 isoform 3
NM_001204274.1 NP_001191203.1 U6 snRNA-associated Sm-like protein LSm2 isoform 4
NM_030597.3 NP_085100.1 U6 snRNA-associated Sm-like protein LSm2 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
8851885 MGI
enables protein kinase binding IDA
IDA: Inferred from direct assay
8851885 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

U6 snRNA-associated Sm-like protein LSm2

  • G7b alternative form

  • LSM2 homolog, U6 small nuclear RNA associated

  • dystrophia myotonica-protein kinase associated protein

  • small ribonuclear protein G7b

  • snRNP core Sm-like protein Sm-x5

  • snRNP core protein SMX5

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07857 LSM2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lsm2 NCBI NCBI:57819