Trim36 - tripartite motif-containing 36 Gene

Also Known as haprin; D18Wsu100e

Species: Mus musculus

Gene Type: protein coding
Gene ID: 28105

Summary

Enables alpha-tubulin binding activity and ubiquitin-protein transferase activity. Involved in regulation of cell cycle. Acts upstream of or within acrosome reaction. Located in acrosomal vesicle. Is expressed in extraembryonic component; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in anencephaly. Orthologous to human TRIM36 (tripartite motif containing 36). [provided by Alliance of Genome Resources, Apr 2022]

Trim36 Products (2)

mRNA Protein Name
NM_001170855.1 NP_001164326.1 E3 ubiquitin-protein ligase Trim36 isoform 2
NM_178872.4 NP_849203.2 E3 ubiquitin-protein ligase Trim36 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables alpha-tubulin binding IDA
IDA: Inferred from direct assay
19232519 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
19232519 MGI
enables ubiquitin-protein transferase activity IDA
IDA: Inferred from direct assay
19232519 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within acrosome reaction IMP
IMP: Inferred from mutant phenotype
12917430 MGI
involved in regulation of cell cycle IMP
IMP: Inferred from mutant phenotype
19232519 MGI
Cellular Component GO Annotation Evidence References Source
located in acrosomal vesicle IDA
IDA: Inferred from direct assay
12917430 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase Trim36

  • RING-type E3 ubiquitin transferase TRIM36

  • acrosome RBCC protein

  • tripartite motif-containing protein 36

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15040 TRIM36 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Trim36 NCBI NCBI:55521