Tomm70a - translocase of outer mitochondrial membrane 70A Gene

Also Known as Tom70; Tomm70; D16Ium22; D16Ium22e; mKIAA0719; D16Wsu109e; 2610044B22Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 28185

Summary

Predicted to be involved in several processes, including negative regulation of cell growth involved in cardiac muscle cell development; positive regulation of interferon-beta production; and regulation of defense response. Located in mitochondrion. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in congestive heart failure. Orthologous to human TOMM70 (translocase of outer mitochondrial membrane 70). [provided by Alliance of Genome Resources, Apr 2022]

Tomm70a Products (1)

mRNA Protein Name
NM_138599.5 NP_613065.2 mitochondrial import receptor subunit TOM70

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15102471 MGI
Cellular Component GO Annotation Evidence References Source
located in mitochondrion IDA
IDA: Inferred from direct assay
23303939 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mitochondrial import receptor subunit TOM70

  • mitochondrial precursor proteins import receptor

  • translocase of outer membrane 70 kDa subunit

  • translocase of outer mitochondrial membrane 70 homolog A

  • translocase of outer mitochondrial membrane protein 70

Tomm70a Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Tomm70 Q9CZW5 Rgs13 Mus musculus Q8K443
Y2H
15102471
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14887 TOMM70 Human Pre-designed siRNA Set A Pre-designed Set / Unkown