Rffl - ring finger and FYVE-like domain containing E3 ubiquitin protein ligase Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 282844

Summary

Predicted to enable enzyme binding activity; p53 binding activity; and ubiquitin protein Ligase activity. Predicted to be involved in several processes, including cellular protein metabolic process; negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis; and negative regulation of signal transduction. Predicted to act upstream of or within intracellular protein transport. Predicted to be located in endosome membrane. Predicted to be active in cytoplasm and plasma membrane. Biomarker of hypertension. Orthologous to human RFFL (ring finger and FYVE like domain containing E3 ubiquitin protein Ligase). [provided by Alliance of Genome Resources, Apr 2022]

Rffl Products (2)

mRNA Protein Name
NM_001004068.2 NP_001004068.1 E3 ubiquitin-protein ligase rififylin isoform 2
NM_001399574.1 NP_001386503.1 E3 ubiquitin-protein ligase rififylin isoform 1
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase rififylin

  • FYVE-RING finger protein Sakura

  • RING finger and FYVE-like domain-containing protein 1

  • RING finger protein SAKURA

  • RING-type E3 ubiquitin transferase rififylin

  • fring

  • ring finger and FYVE like domain containing protein

  • ring finger and FYVE-like domain

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11871 RFFL Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rffl NCBI NCBI:117584