MLNR - motilin receptor Gene

Homo sapiens

Also known as GPR38; MTLR1

Gene ID: 2862 | Gene type: protein coding

About MLNR

Cytogenetic location: 13q14.2 Genomic coordinates (GRCh38): 13:49,220,338-49,222,377 (from NCBI)

This gene has 1 transcript (splice variant), 169 orthologues and 15 paralogues. Low expression observed in reference dataset.

Summary

Motilin is a 22 amino acid peptide hormone expressed throughout the gastrointestinal (GI) tract. The protein encoded by this gene is a Motilin Receptor which is a member of the G-protein coupled receptor 1 family. This member is a multi-pass transmembrane protein, and is an important therapeutic target for the treatment of hypomotility disorders. [provided by RefSeq, Aug 2011]

MLNR Products(1)

mRNA	Protein	Name
NM_001507.1	NP_001498.1	motilin receptor

MLNR Protein Structure

7tm_1

0
100
200
300
412 a.a.

Protein Preferred Names

Protein Names

motilin receptor

G protein-coupled receptor 38

Related Diseases

Diseases

Alias

Superior Mesenteric Artery Syndrome

Wilkie Syndrome	Wilkie'S Syndrome
Arteriomesenteric Duodenal Compression Syndrome	Cast Syndrome
Vascular Compression Of The Duodenum	Smas
Arteriomesenteric Compression Of Duodenojejunal Flexure

Intestinal Pseudo-Obstruction

Chronic Intestinal Pseudoobstruction	Chronic Intestinal Pseudo-Obstruction
Cipo	Neuronal Intestinal Dysplasia
Hollow Visceral Myopathy	Familial Visceral Neuropathy
Paralytic Ileus	Intestinal Pseudoobstruction
Chronic Idiopathic Intestinal Pseudo-Obstruction	Ciip
Congenital Short Bowel Syndrome	Enteric Neuropathy
Familial Visceral Myopathy	Ipo
Pseudo-Obstruction Of Intestine	Pseudointestinal Obstruction Syndrome
Pseudoobstructive Syndrome	Congenital Idiopathic Intestinal Pseudoobstruction
Visceral Myopathy, Familial

Constipation

Diabetic Autonomic Neuropathy

Diabetic Neuropathies

Pylorospasm

Gastroparesis

Gastroparesis Syndrome	Delayed Gastric Emptying
Gastric Atonia	Gastroparalysis

Benign Essential Hypertension

Hypertrophic Pyloric Stenosis

Congenital Hypertrophic Pyloric Stenosis	Pyloric Stenosis, Hypertrophic
Congenital Or Infantile Stricture Of Pylorus	Achalasia Of The Pylorus
Congenital Hypertrophy Of The Pylorus	Infantile Hypertrophy Of The Pylorus
Infantile Constriction Of The Pylorus	Congenital Stenosis Of The Pylorus
Congenital Constriction Of The Pylorus	Congenital Stricture Of The Pylorus
Infantile Hypertrophic Pyloric Stenosis	Infantile Stenosis Of The Pylorus
Infantile Stricture Of The Pylorus	Congenital Or Infantile Constriction Of Pylorus
Infantile Pyloric Obstruction	Infantile Pyloric Hypertrophy
Pylorus Achalasia	Pyloric Constriction
Infantile Pyloric Stricture	Infantile Pyloric Stenosis
Congenital Spasm Of Pylorus	Congenital Pylorospasm
Congenital Pyloric Stricture	Congenital Pyloric Spasm
Congenital Or Infantile Spasm Of Pylorus	Congenital Or Infantile Obstruction Of Pylorus
Congenital Pyloric Stenosis

Functional Colonic Disease

Colonic Diseases, Functional

Functional Gastric Disease

Rumination Disorder

Rumination Syndrome	Psychogenic Rumination
Rumination Disorders

Lung Occult Small Cell Carcinoma

Occult Small Cell Carcinoma Of Lung

Occult Small Cell Carcinoma Of The Lung

Gallbladder Disease

Gallbladder Diseases	Gall Bladder
Gall Bladder Diseases	Abnormal Gallbladder Function

Colonic Pseudo-Obstruction

Primary Chronic Pseudo-Obstruction Of Colon

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08499	MLNR Human Pre-designed siRNA Set A		/	Unkown
HY-RS08500	Mlnr Rat Pre-designed siRNA Set A		/	Unkown

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