Dlgap3 - DLG associated protein 3 Gene

Rattus norvegicus

Also known as Dap3; DAP-3; SAPAP3

Gene ID: 286923 | Gene type: protein coding

About Dlgap3

Summary

Enables PDZ domain binding activity; molecular adaptor activity; and scaffold protein binding activity. Involved in protein-containing complex assembly. Located in several cellular components, including dendritic spine; neuronal cell body; and postsynaptic density. Orthologous to human DLGAP3 (DLG associated protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Dlgap3 Products(3)

mRNA	Protein	Name
NM_001276304.1	NP_001263233.1	disks large-associated protein 3 isoform 2
NM_001301876.3	NP_001288805.1	disks large-associated protein 3 isoform 3
NM_173138.6	NP_775161.2	disks large-associated protein 3 isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables PDZ domain binding	IPI IPI: Inferred from physical interaction	10433269	RGD
enables molecular adaptor activity	IPI IPI: Inferred from physical interaction	10433269	RGD
enables protein binding	IPI IPI: Inferred from physical interaction	12586822	RGD
enables protein domain specific binding	IDA IDA: Inferred from direct assay	9115257	RGD
enables scaffold protein binding	IPI IPI: Inferred from physical interaction	10433269	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in protein-containing complex assembly	IDA IDA: Inferred from direct assay	10433269	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in dendritic spine	IDA IDA: Inferred from direct assay	15207911	RGD
located in neuronal cell body	IDA IDA: Inferred from direct assay	9115257	RGD
located in postsynaptic density	IDA IDA: Inferred from direct assay	10433269	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

disks large-associated protein 3

PSD-95/SAP90-associated protein-3	PSD-95/SAP90-binding protein 3
SAP90/PSD-95-associated protein 3	discs large homolog associated protein 3

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03803	DLGAP3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Dlgap3	NCBI	NCBI:58512

Name
Email *

	Sorry, but the email address you supplied was invalid.