1. Gene
  2. Wrap53 - WD repeat containing, antisense to TP53 Gene

Wrap53 - WD repeat containing, antisense to TP53 Gene

Rattus norvegicus

Also known as Wdr79

Gene ID: 287432 | Gene type: protein coding

About Wrap53

Summary

Predicted to enable several functions, including chaperone binding activity; Telomerase RNA binding activity; and ubiquitin protein Ligase binding activity. Predicted to be involved in several processes, including RNA localization to Cajal body; positive regulation of DNA metabolic process; and telomere organization. Predicted to be located in cytosol; nuclear body; and site of double-strand break. Predicted to be part of Telomerase holoenzyme complex. Predicted to be active in Cajal body. Human ortholog(s) of this gene implicated in autosomal recessive dyskeratosis congenita 3; colorectal cancer; head and neck squamous cell carcinoma; lung non-small cell carcinoma; and ovarian Cancer. Orthologous to human WRAP53 (WD repeat containing antisense to TP53). [provided by Alliance of Genome Resources, Apr 2022]

Wrap53 Products(1)

mRNA Protein Name
NM_001007610.1 NP_001007611.1 telomerase Cajal body protein 1
Protein Preferred Names Protein Names

telomerase Cajal body protein 1

WD repeat domain 79

WD repeat-containing protein 79

WD repeat-containing protein WRAP53

WD40 repeat-containing protein antisense to TP53 gene homolog

WD40 repeat-containing protein encoded by RNA antisense to p53

Orthologs Information

Species Symbol Source ID
Homo sapiens Wrap53 NCBI NCBI:55135