Poldip2 - DNA polymerase delta interacting protein 2 Gene

Rattus norvegicus

Also known as PDIP38

Gene ID: 287544 | Gene type: protein coding

About Poldip2

Summary

Predicted to enable DNA binding activity. Involved in several processes, including positive regulation of Rho guanyl-nucleotide exchange factor activity; positive regulation of actin filament binding activity; and positive regulation of focal adhesion assembly. Located in several cellular components, including cell-cell junction; midbody; and mitotic spindle. Orthologous to human POLDIP2 (DNA Polymerase delta interacting protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Poldip2 Products(1)

mRNA	Protein	Name
NM_001401983.1	NP_001388912.1	polymerase delta-interacting protein 2

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	17623671	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in mitotic spindle assembly	IMP IMP: Inferred from mutant phenotype	18843206	RGD
involved in positive regulation of Rho guanyl-nucleotide exchange factor activity	IDA IDA: Inferred from direct assay	30726115	RGD
involved in positive regulation of focal adhesion assembly	IMP IMP: Inferred from mutant phenotype	30354218	RGD
involved in positive regulation of mitotic cytokinesis	IMP IMP: Inferred from mutant phenotype	30726115	RGD
involved in vascular associated smooth muscle cell proliferation	IMP IMP: Inferred from mutant phenotype	30237457	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in cell-cell junction	IDA IDA: Inferred from direct assay	17623671	RGD
located in midbody	IDA IDA: Inferred from direct assay	18843206	RGD
located in mitotic spindle	IDA IDA: Inferred from direct assay	18843206	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

polymerase delta-interacting protein 2

DNA-directed polymerase delta interacting protein 2	polymerase (DNA) delta interacting protein 2
polymerase (DNA-directed), delta interacting protein 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10823	POLDIP2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Poldip2	NCBI	NCBI:26073

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