Lrrc8c - leucine rich repeat containing 8 VRAC subunit C Gene

Also Known as RGD1306585

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 289443

Summary

Contributes to volume-sensitive anion channel activity. Involved in aspartate transmembrane transport; cellular response to osmotic stress; and taurine transport. Is integral component of plasma membrane. Part of ion channel complex. Orthologous to human LRRC8C (leucine rich repeat containing 8 VRAC subunit C). [provided by Alliance of Genome Resources, Apr 2022]

Lrrc8c Products (1)

mRNA Protein Name
NM_001037179.1 NP_001032256.1 volume-regulated anion channel subunit LRRC8C

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
contributes to volume-sensitive anion channel activity IMP
IMP: Inferred from mutant phenotype
28833202 RGD
Biological Process GO Annotation Evidence References Source
involved in aspartate transmembrane transport IMP
IMP: Inferred from mutant phenotype
28833202 RGD
involved in cellular response to osmotic stress IMP
IMP: Inferred from mutant phenotype
28833202 RGD
involved in taurine transmembrane transport IMP
IMP: Inferred from mutant phenotype
28833202 RGD
Cellular Component GO Annotation Evidence References Source
part of monoatomic ion channel complex IMP
IMP: Inferred from mutant phenotype
28833202 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

volume-regulated anion channel subunit LRRC8C

  • leucine rich repeat containing 8 family, member C

  • leucine-rich repeat-containing protein 8C

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07829 LRRC8C Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lrrc8c NCBI NCBI:84230