Bsn - bassoon (presynaptic cytomatrix protein) Gene

Also Known as Znf231

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29138

Summary

Enables dynein light chain binding activity and transcription corepressor binding activity. Involved in presynaptic active zone assembly; regulation of ubiquitin protein Ligase activity; and retrograde axonal transport. Located in several cellular components, including axon cytoplasm; cytoplasmic vesicle; and Cytoskeleton of presynaptic active zone. Is extrinsic component of membrane. Is active in several cellular components, including GABA-ergic synapse; hippocampal mossy fiber to CA3 synapse; and presynaptic active zone cytoplasmic component. Colocalizes with synaptic membrane. Orthologous to human BSN (bassoon presynaptic cytomatrix protein). [provided by Alliance of Genome Resources, Apr 2022]

Bsn Products (1)

mRNA Protein Name
NM_019146.2 NP_062019.2 protein bassoon

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables dynein light chain binding IPI
IPI: Inferred from physical interaction
19380881 RGD
enables enzyme inhibitor activity IDA
IDA: Inferred from direct assay
21700703 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
12163476 RGD
enables transcription corepressor binding IPI
IPI: Inferred from physical interaction
25652077 RGD
Biological Process GO Annotation Evidence References Source
involved in axo-dendritic transport IDA
IDA: Inferred from direct assay
19380881 RGD
involved in modulation of chemical synaptic transmission IDA
IDA: Inferred from direct assay
21700703 RGD
involved in presynaptic active zone assembly IDA
IDA: Inferred from direct assay
22875941 RGD
involved in regulation of ubiquitin protein ligase activity IDA
IDA: Inferred from direct assay
23403927 RGD
involved in retrograde axonal transport IDA
IDA: Inferred from direct assay
19380881 RGD
involved in synapse organization IDA
IDA: Inferred from direct assay
23403927 RGD
Cellular Component GO Annotation Evidence References Source
is active in GABA-ergic synapse IDA
IDA: Inferred from direct assay
10340516 RGD
located in Golgi-associated vesicle IDA
IDA: Inferred from direct assay
22875941 RGD
located in axon cytoplasm IDA
IDA: Inferred from direct assay
19380881 RGD
located in cell cortex IDA
IDA: Inferred from direct assay
19380881 RGD
located in cytoskeleton of presynaptic active zone IDA
IDA: Inferred from direct assay
9679147 RGD
located in excitatory synapse IDA
IDA: Inferred from direct assay
19730411 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
9679147 RGD
is active in hippocampal mossy fiber to CA3 synapse IDA
IDA: Inferred from direct assay
9679147 RGD
located in inhibitory synapse IDA
IDA: Inferred from direct assay
11596050 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
16373352 RGD
located in piccolo-bassoon transport vesicle IDA
IDA: Inferred from direct assay
19380881 RGD
located in presynaptic active zone IDA
IDA: Inferred from direct assay
15978582 RGD
is active in presynaptic active zone cytoplasmic component IDA
IDA: Inferred from direct assay
9679147 RGD
located in ribbon synapse IDA
IDA: Inferred from direct assay
11596050 RGD
located in synaptic membrane IDA
IDA: Inferred from direct assay
19380881 RGD
located in synaptic vesicle IDA
IDA: Inferred from direct assay
26212709 RGD
located in trans-Golgi network IDA
IDA: Inferred from direct assay
16373352 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein bassoon

  • neuronal double zinc finger protein

  • zinc finger protein 231

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-114591 Spiromesifen Inhibitor 99.42% Unkown
HY-114591S Spiromesifen-d9 / Unkown
HY-RS01644 BSN Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bsn NCBI NCBI:8927