BSN - bassoon presynaptic cytomatrix protein Gene

Also Known as ZNF231

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 8927

About BSN

Cytogenetic location: 3p21.31 Genomic coordinates (GRCh38): 3:49,554,477-49,673,130 (from NCBI)

This gene has 2 transcripts (splice variants), 274 orthologues and 1 paralogue. Biased expression in brain (RPKM 13.0), testis (RPKM 2.3) and 1 other tissue.

Summary

Neurotransmitters are released from a specific site in the axon terminal called the active zone, which is composed of synaptic vesicles and a meshwork of Cytoskeleton underlying the plasma membrane. The protein encoded by this gene is thought to be a scaffolding protein involved in organizing the presynaptic Cytoskeleton. The gene is expressed primarily in neurons in the brain. A similar gene product in rodents is concentrated in the active zone of axon terminals and tightly associated with cytoskeletal structures, and is essential for regulating neurotransmitter release from a subset of synapses. [provided by RefSeq, Jul 2008]

BSN Products (1)

mRNA Protein Name
NM_003458.4 NP_003449.2 protein bassoon

BSN Protein Structure

zf-piccolo

zf-piccolo: Piccolo Zn-finger (167 - 226)

zf-piccolo

zf-piccolo: Piccolo Zn-finger (462 - 521)

  • 0
  • 700
  • 1400
  • 2100
  • 2800
  • 3500
  • 3926 a.a.
Protein Preferred Names Protein Names

protein bassoon

  • neuronal double zinc finger protein

Related Diseases

Diseases Alias
Cork-Handlers' Disease

  • Suberosis

  • Cork-Handlers' Disease Or Lung

  • Cork-Handlers' Lung

  • Corkhandler Disease

  • Corkworker Lung

  • Corkhandler Hypersensitivity Pneumonitis

  • Cork-Handler Disease

  • Cork-Handler Lung
Cone-Rod Dystrophy 7

  • CORD7

  • Dystrophy, Cone-Rod, Type 7

  • Retinitis Pigmentosa 7
Atrial Septal Defect 2

  • ASD2

  • Atrial Heart Septal Defect 2

  • Atrial Septal Defect-2

  • Asd Ii

  • Septal Defect, Atrial, Type 2
Congenital Stationary Night Blindness

  • Night Blindness, Congenital Stationary

  • Congenital Essential Nyctalopia

  • Oguchi Disease

  • Blindness, Night, Stationary, Congenital
Schizophrenia

  • SCZD

  • Schizophrenia With Or Without An Affective Disorder

  • Schizophrenia 12

  • Schizophrenia, Susceptibility To

  • Schizophrenia-1

  • Dementia Praecox

  • Schizophrenia 1
Cone-Rod Dystrophy 2

  • Cone-Rod Dystrophy

  • CORD2

  • Cone-Rod Retinal Dystrophy

  • Rcrd2

  • Cone-Rod Retinal Dystrophy 2

  • Crd2

  • Cord

  • Crd

  • Retinal Cone-Rod Dystrophy

  • Cone-Rod Retinal Dystrophy-2

  • Retinal Cone-Rod Dystrophy 2

  • Tapetoretinal Degeneration

  • Cone-Rod Degeneration

  • Cone Rod Dystrophy

  • Dystrophy, Cone-Rod

  • Dystrophy, Cone-Rod, Type 2

  • Retinitis Pigmentosa

  • Retinitis Pigmentosa 2

  • Progressive Cone-Rod Dystrophy
Retinitis Pigmentosa

  • RP

  • Rod-Cone Dystrophy

  • Autosomal Recessive Retinitis Pigmentosa

  • Non-Syndromic Retinitis Pigmentosa

  • Pericentral Pigmentary Retinopathy

  • Pigmentary Retinopathy

  • Tapetoretinal Degeneration

  • Rcd

  • Retinitis Pigmentosa Autosomal Recessive

  • ARRP

  • Retinitis Pigmentosa, Autosomal Recessive

  • Retinitis Pigmentosa 1
Fundus Dystrophy

  • Retinal Dystrophy

  • Retinal Dystrophies

  • Dystrophy, Retinal
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-114591 Spiromesifen Inhibitor 99.42% Unkown
HY-114591S Spiromesifen-d9 / Unkown
HY-RS01644 BSN Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris BSN VGNC VGNC:54578
Mus musculus BSN MGD MGI:1277955
Rattus norvegicus BSN RGD RGD:2223
Felis catus BSN VGNC VGNC:60188
Bos taurus BSN VGNC VGNC:59321
Macaca mulatta BSN VGNC VGNC:70284
Others BSN NCBI