Katnb1 - katanin regulatory subunit B1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 291852

Summary

Predicted to enable ATPase regulator activity; dynein complex binding activity; and protein heterodimerization activity. Involved in microtubule severing; positive regulation of cell death; and positive regulation of neuron projection development. Located in growth cone; midbody; and neuronal cell body. Human ortholog(s) of this gene implicated in lissencephaly 6. Orthologous to human KATNB1 (katanin regulatory subunit B1). [provided by Alliance of Genome Resources, Apr 2022]

Katnb1 Products (1)

mRNA Protein Name
NM_001024746.2 NP_001019917.1 katanin p80 WD40 repeat-containing subunit B1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
17351128 RGD
Biological Process GO Annotation Evidence References Source
involved in microtubule severing IDA
IDA: Inferred from direct assay
15944385 RGD
involved in positive regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
17351128 RGD
involved in positive regulation of neuron projection development IDA
IDA: Inferred from direct assay
15944385 RGD
Cellular Component GO Annotation Evidence References Source
located in axon IDA
IDA: Inferred from direct assay
15944385 RGD
located in growth cone IDA
IDA: Inferred from direct assay
15944385 RGD
located in midbody IDA
IDA: Inferred from direct assay
17351128 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
15944385 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

katanin p80 WD40 repeat-containing subunit B1

  • katanin p80 (WD repeat containing) subunit B 1

  • katanin p80 (WD40-containing) subunit B 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07087 KATNB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Katnb1 NCBI NCBI:10300