2. Gene
  3. Actc1 - actin, alpha, cardiac muscle 1 Gene

Actc1 - actin, alpha, cardiac muscle 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 29275 | Gene type: protein coding

About Actc1

Summary

Predicted to enable ATP binding activity; microfilament motor activity; and Myosin binding activity. Involved in cardiac muscle contraction; response to ethanol; and response to xenobiotic stimulus. Predicted to be located in several cellular components, including I band; filopodium; and lamellipodium. Predicted to be part of dynactin complex. Predicted to be active in actin filament; glutamatergic synapse; and sarcomere. Biomarker of hypertension. Human ortholog(s) of this gene implicated in atrial heart septal defect 5; dilated cardiomyopathy; dilated cardiomyopathy 1R; and hypertrophic cardiomyopathy 11. Orthologous to human ACTC1 (actin alpha cardiac muscle 1). [provided by Alliance of Genome Resources, Apr 2022]

Actc1 Products(1)

mRNA Protein Name
NM_019183.1 NP_062056.1 actin, alpha cardiac muscle 1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
12898519 RGD
Biological Process GO Annotation Evidence Reference Source
involved in cardiac muscle contraction IDA
IDA: Inferred from direct assay
14551059 RGD
involved in response to ethanol IEP
IEP: Inferred from expression pattern
15690316 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
16343576 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

actin, alpha cardiac muscle 1

actin, alpha, cardiac 1

alpha-actin cardiac

alpha-cardiac actin

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00217 ACTC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Actc1 NCBI NCBI:70