2. Gene
  3. Cyp2c11 - cytochrome P450, subfamily 2, polypeptide 11 Gene

Cyp2c11 - cytochrome P450, subfamily 2, polypeptide 11 Gene

  • Gene
  • Protein
  • Agent
Rattus norvegicus

Also known as Cyp2c; CYP2CII; Cyp2c11l

Gene ID: 29277 | Gene type: protein coding

About Cyp2c11

Summary

Enables arachidonic acid 11,12-epoxygenase activity; arachidonic acid 14,15-epoxygenase activity; and testosterone 16-alpha-hydroxylase activity. Involved in epoxygenase P450 pathway and icosanoid biosynthetic process. Located in endoplasmic reticulum membrane. Biomarker of end stage renal disease; hypertension; and mental depression. Orthologous to human CYP2C18 (Cytochrome P450 family 2 subfamily C member 18). [provided by Alliance of Genome Resources, Apr 2022]

Cyp2c11 Products(2)

mRNA Protein Name
NM_019184.2 NP_062057.2 cytochrome P450 2C11 precursor
NM_019184.2 NP_062057.2 cytochrome P450 2C11 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables arachidonate 11,12-epoxygenase activity IDA
IDA: Inferred from direct assay
10491410 RGD
enables arachidonate 14,15-epoxygenase activity IDA
IDA: Inferred from direct assay
10491410 RGD
enables monooxygenase activity IDA
IDA: Inferred from direct assay
15766564 RGD
enables testosterone 16-alpha-hydroxylase activity IDA
IDA: Inferred from direct assay
2434473 RGD
enables testosterone 16-alpha-hydroxylase activity IMP
IMP: Inferred from mutant phenotype
8611037 RGD
Biological Process GO Annotation Evidence Reference Source
involved in epoxygenase P450 pathway IDA
IDA: Inferred from direct assay
10491410 RGD
involved in icosanoid biosynthetic process IDA
IDA: Inferred from direct assay
15766564 RGD
Cellular Component GO Annotation Evidence Reference Source
located in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
2434473 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cytochrome P450 2C11

CYPIIC11

P-450(M-1)

P450-UT-A

P450H

UT-2

cytochrome P-450(M-1)

cytochrome P450 2C11-like

cytochrome P450, 2c29

cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 11

cytochrome P450-UT-2

cytochrome P450-UT-A

cytochrome P450H

Related Agents

Approval
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-N0482 Phillyrin 98.82% Unkown
Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B1351 Bilberry Extract / Unkown