Zfp36l1 - zinc finger protein 36, C3H type-like 1 Gene

Also Known as Brf1; ERF1; cMG1; Berg36; TIS11b

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29344

Summary

Enables mRNA 3'-UTR AU-rich region binding activity. Involved in nuclear-transcribed mRNA catabolic process, deadenylation-independent decay and positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay. Acts upstream of or within mRNA catabolic process. Located in cytosol. Orthologous to human ZFP36L1 (ZFP36 ring finger protein like 1). [provided by Alliance of Genome Resources, Apr 2022]

Zfp36l1 Products (1)

mRNA Protein Name
NM_017172.2 NP_058868.1 mRNA decay activator protein ZFP36L1
Molecular Function GO Annotation Evidence References Source
enables mRNA 3'-UTR AU-rich region binding IDA
IDA: Inferred from direct assay
12748283 RGD
enables mRNA 3'-UTR AU-rich region binding IMP
IMP: Inferred from mutant phenotype
10751406 RGD
enables mRNA binding IDA
IDA: Inferred from direct assay
10751406 RGD
Cellular Component GO Annotation Evidence References Source
located in cytosol IDA
IDA: Inferred from direct assay
10751406 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mRNA decay activator protein ZFP36L1

  • EGF-inducible protein CMG1

  • TPA-induced sequence 11b

  • ZFP36-like 1

  • butyrate response factor 1

  • zinc finger protein 36, C3H1 type-like 1

Orthologs Information

Species Symbol Source ID
Homo sapiens Zfp36l1 NCBI NCBI:677