Slc22a3 - solute carrier family 22 member 3 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29504

Summary

Enables ion transmembrane transporter activity and toxin transmembrane transporter activity. Involved in cation transport; organic anion transport; and quaternary ammonium group transport. Predicted to be located in neuronal cell body and plasma membrane. Orthologous to human SLC22A3 (solute carrier family 22 member 3). [provided by Alliance of Genome Resources, Apr 2022]

Slc22a3 Products (1)

mRNA Protein Name
NM_019230.1 NP_062103.1 solute carrier family 22 member 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables dopamine:sodium symporter activity IDA
IDA: Inferred from direct assay
9830022 RGD
enables monoamine transmembrane transporter activity IDA
IDA: Inferred from direct assay
16581093 RGD
enables neurotransmitter transmembrane transporter activity IDA
IDA: Inferred from direct assay
16581093 RGD
enables organic anion transmembrane transporter activity IDA
IDA: Inferred from direct assay
20924140 RGD
enables organic cation transmembrane transporter activity IDA
IDA: Inferred from direct assay
9632645 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
11238452 RGD
enables quaternary ammonium group transmembrane transporter activity IMP
IMP: Inferred from mutant phenotype
9632645 RGD
enables spermidine transmembrane transporter activity IDA
IDA: Inferred from direct assay
23458604 RGD
enables toxin transmembrane transporter activity IDA
IDA: Inferred from direct assay
9830022 RGD
Biological Process GO Annotation Evidence References Source
involved in dopamine transport IDA
IDA: Inferred from direct assay
9830022 RGD
involved in epinephrine transport IDA
IDA: Inferred from direct assay
16581093 RGD
involved in histamine transport IDA
IDA: Inferred from direct assay
16581093 RGD
involved in norepinephrine transport IDA
IDA: Inferred from direct assay
16581093 RGD
involved in organic anion transport IDA
IDA: Inferred from direct assay
20924140 RGD
involved in organic cation transport IDA
IDA: Inferred from direct assay
9632645 RGD
involved in quaternary ammonium group transport IMP
IMP: Inferred from mutant phenotype
9632645 RGD
involved in serotonin transport IDA
IDA: Inferred from direct assay
16581093 RGD
involved in spermidine transport IDA
IDA: Inferred from direct assay
23458604 RGD
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
15817714 RGD
located in endomembrane system IDA
IDA: Inferred from direct assay
27659446 RGD
located in mitochondrial membrane IDA
IDA: Inferred from direct assay
27659446 RGD
located in plasma membrane IDA
IDA: Inferred from direct assay
27659446 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

solute carrier family 22 member 3

  • organic cation transporter 3

  • solute carrier family 22 (extraneuronal monoamine transporter), member 3

  • solute carrier family 22 (organic cation transporter), member 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13074 SLC22A3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc22a3 NCBI NCBI:6581