Slc22a6 - solute carrier family 22 member 6 Gene

Also Known as Oat1; Paht; Roat1; Orctl1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29509

Summary

Enables chloride ion binding activity; identical protein binding activity; and secondary active transmembrane transporter activity. Involved in response to organic cyclic compound and sodium-independent organic anion transport. Acts upstream of or within organic anion transport. Located in caveola. Part of protein-containing complex. Orthologous to human SLC22A6 (solute carrier family 22 member 6). [provided by Alliance of Genome Resources, Apr 2022]

Slc22a6 Products (1)

mRNA Protein Name
NM_017224.2 NP_058920.1 solute carrier family 22 member 6

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables antiporter activity IDA
IDA: Inferred from direct assay
9228014 RGD
enables chloride ion binding IDA
IDA: Inferred from direct assay
18361503 RGD
enables identical protein binding IPI
IPI: Inferred from physical interaction
18361503 RGD
enables organic anion transmembrane transporter activity IDA
IDA: Inferred from direct assay
9228014 RGD
enables prostaglandin transmembrane transporter activity IDA
IDA: Inferred from direct assay
9228014 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
16000875 RGD
enables sodium-independent organic anion transmembrane transporter activity IDA
IDA: Inferred from direct assay
9228014 RGD
Biological Process GO Annotation Evidence References Source
involved in metanephric proximal tubule development IEP
IEP: Inferred from expression pattern
30645697 RGD
acts upstream of or within organic anion transport IDA
IDA: Inferred from direct assay
15068970 RGD
involved in prostaglandin transport IDA
IDA: Inferred from direct assay
9228014 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
16925582 RGD
involved in sodium-independent organic anion transport IDA
IDA: Inferred from direct assay
9228014 RGD
Cellular Component GO Annotation Evidence References Source
located in caveola IDA
IDA: Inferred from direct assay
16000875 RGD
part of protein-containing complex IDA
IDA: Inferred from direct assay
16000875 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

solute carrier family 22 member 6

  • organic anion transporter 1

  • organic cationic transporter-like 1

  • rROAT1

  • renal organic anion transporter 1

  • solute carrier family 22 (organic anion transporter), member 6

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13078 SLC22A6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc22a6 NCBI NCBI:9356