Ighmbp2 - immunoglobulin mu DNA binding protein 2 Gene

Also Known as AEP

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29532

Summary

Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in several cellular components, including growth cone; neuronal cell body; and nuclear body. Predicted to be part of ribonucleoprotein complex. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2S and distal spinal muscular atrophy 1. Orthologous to human IGHMBP2 (immunoglobulin mu DNA binding protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Ighmbp2 Products (1)

mRNA Protein Name
NM_031586.2 NP_113774.2 DNA-binding protein SMUBP-2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
15358184 RGD
Biological Process GO Annotation Evidence References Source
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
15358184 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DNA-binding protein SMUBP-2

  • ATP-dependent helicase IGHMBP2

  • antifreeze enhancer-binding protein ortholog

  • immunoglobulin S mu binding protein 2

  • immunoglobulin mu binding protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06638 IGHMBP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ighmbp2 NCBI NCBI:3508