Amigo1 - adhesion molecule with Ig like domain 1 Gene

Rattus norvegicus

Also known as Amigo

Gene ID: 295365 | Gene type: protein coding

About Amigo1

Summary

Predicted to enable Potassium Channel regulator activity. Involved in several processes, including cellular response to L-glutamate; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; and nervous system development. Located in neuronal cell body and pericellular basket. Is integral component of membrane. Orthologous to human AMIGO1 (adhesion molecule with Ig like domain 1). [provided by Alliance of Genome Resources, Apr 2022]

Amigo1 Products(2)

mRNA	Protein	Name
NM_001412551.1	NP_001399480.1	amphoterin-induced protein 1 precursor
NM_206881.1	NP_996764.1	amphoterin-induced protein 1 precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	12629050	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in axonal fasciculation	IDA IDA: Inferred from direct assay	12629050	RGD
involved in axonogenesis	IDA IDA: Inferred from direct assay	12629050	RGD
involved in cellular response to L-glutamate	IDA IDA: Inferred from direct assay	22056818	RGD
involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	IPI IPI: Inferred from physical interaction	12629050	RGD
involved in homophilic cell adhesion via plasma membrane adhesion molecules	IPI IPI: Inferred from physical interaction	12629050	RGD
involved in myelination	IEP IEP: Inferred from expression pattern	12629050	RGD
involved in neuron projection fasciculation	IDA IDA: Inferred from direct assay	12629050	RGD
involved in positive regulation of axonogenesis	IDA IDA: Inferred from direct assay	12629050	RGD
involved in positive regulation of neuron projection development	IDA IDA: Inferred from direct assay	12629050	RGD
involved in positive regulation of voltage-gated potassium channel activity	IMP IMP: Inferred from mutant phenotype	22056818	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in neuronal cell body	IDA IDA: Inferred from direct assay	12629050	RGD
located in pericellular basket	IDA IDA: Inferred from direct assay	12629050	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

amphoterin-induced protein 1

AMIGO-1	alivin-2
amphoretin-induced gene and ORF	transmembrane protein AMIGO

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00657	AMIGO1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Amigo1	NCBI	NCBI:57463

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