2. Gene
  3. Atp2b3 - ATPase plasma membrane Ca2+ transporting 3 Gene

Atp2b3 - ATPase plasma membrane Ca2+ transporting 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Pmca3

Gene ID: 29599 | Gene type: protein coding

About Atp2b3

Summary

Enables PDZ domain binding activity. Involved in brain development and neural retina development. Located in membrane raft and parallel fiber. Is active in glutamatergic synapse and parallel fiber to Purkinje cell synapse. Is integral component of presynaptic membrane. Human ortholog(s) of this gene implicated in X-linked spinocerebellar ataxia 1. Orthologous to human ATP2B3 (ATPase plasma membrane Ca2+ transporting 3). [provided by Alliance of Genome Resources, Apr 2022]

Atp2b3 Products(1)

mRNA Protein Name
NM_133288.2 NP_579822.1 plasma membrane calcium-transporting ATPase 3
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables PDZ domain binding IPI
IPI: Inferred from physical interaction
16554037 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
12763866 RGD
Biological Process GO Annotation Evidence Reference Source
involved in neural retina development IEP
IEP: Inferred from expression pattern
16079002 RGD
Cellular Component GO Annotation Evidence Reference Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
17183553 RGD
located in parallel fiber IDA
IDA: Inferred from direct assay
17183553 RGD
is active in parallel fiber to Purkinje cell synapse IDA
IDA: Inferred from direct assay
17183553 RGD
located in parallel fiber to Purkinje cell synapse IDA
IDA: Inferred from direct assay
17183553 RGD
is active in presynaptic membrane IDA
IDA: Inferred from direct assay
17183553 RGD
located in presynaptic membrane IDA
IDA: Inferred from direct assay
17183553 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

plasma membrane calcium-transporting ATPase 3

ATPase, Ca++ transporting, plasma membrane 3

plasma membrane calcium ATPase

plasma membrane calcium pump

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01196 ATP2B3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Atp2b3 NCBI NCBI:492