Arfgef2 - ADP ribosylation factor guanine nucleotide exchange factor 2 Gene

Also Known as Big2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 296380

Summary

Enables GABA Receptor binding activity and Myosin binding activity. Involved in exocytosis. Located in several cellular components, including axonemal microtubule; dendritic spine; and trans-Golgi network. Human ortholog(s) of this gene implicated in periventricular nodular heterotopia. Orthologous to human ARFGEF2 (ADP ribosylation factor guanine nucleotide exchange factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Arfgef2 Products (1)

mRNA Protein Name
NM_181083.2 NP_851597.2 brefeldin A-inhibited guanine nucleotide-exchange protein 2
Protein Preferred Names Protein Names

brefeldin A-inhibited guanine nucleotide-exchange protein 2

  • ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)

  • Brefeldin A-inhibited guanine nucleotide-exchange factor 2

  • brefeldin A-inhibited GEP 2

Arfgef2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Arfgef2 Q7TSU1 Gabrb3 Rattus norvegicus P63079
Y2H
15198677
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00903 ARFGEF2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arfgef2 NCBI NCBI:10564