Arfgef2 - ADP ribosylation factor guanine nucleotide exchange factor 2 Gene

Rattus norvegicus

Also known as Big2

Gene ID: 296380 | Gene type: protein coding

About Arfgef2

Summary

Enables GABA Receptor binding activity and Myosin binding activity. Involved in exocytosis. Located in several cellular components, including axonemal microtubule; dendritic spine; and trans-Golgi network. Human ortholog(s) of this gene implicated in periventricular nodular heterotopia. Orthologous to human ARFGEF2 (ADP ribosylation factor guanine nucleotide exchange factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Arfgef2 Products(1)

mRNA	Protein	Name
NM_181083.2	NP_851597.2	brefeldin A-inhibited guanine nucleotide-exchange protein 2

Protein Preferred Names

Protein Names

brefeldin A-inhibited guanine nucleotide-exchange protein 2

ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)	Brefeldin A-inhibited guanine nucleotide-exchange factor 2
brefeldin A-inhibited GEP 2

Arfgef2 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Arfgef2	Q7TSU1	Gabrb3	Rattus norvegicus	P63079	Y2H	15198677

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00903	ARFGEF2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Arfgef2	NCBI	NCBI:10564

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