Sh3bp1 - SH3-domain binding protein 1 Gene

Rattus norvegicus

Gene ID: 300067 | Gene type: protein coding

About Sh3bp1

Summary

Enables GTPase activator activity. Involved in cell migration; filopodium assembly; and positive regulation of GTPase activity. Located in cell leading edge. Orthologous to human SH3BP1 (SH3 domain binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Sh3bp1 Products(1)

mRNA	Protein	Name
NM_001171981.1	NP_001165452.1	SH3 domain-binding protein 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables GTPase activator activity	IMP IMP: Inferred from mutant phenotype	21658605	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in cell migration	IMP IMP: Inferred from mutant phenotype	21658605	RGD
involved in filopodium assembly	IMP IMP: Inferred from mutant phenotype	21658605	RGD
involved in positive regulation of GTPase activity	IMP IMP: Inferred from mutant phenotype	21658605	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in cell leading edge	IDA IDA: Inferred from direct assay	21658605	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

SH3 domain-binding protein 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12829	SH3BGRL3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS12830	SH3BP1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Sh3bp1	NCBI	NCBI:23616

Name
Email *

	Sorry, but the email address you supplied was invalid.