Sh3bp1 - SH3-domain binding protein 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 300067

Summary

Enables GTPase activator activity. Involved in cell migration; filopodium assembly; and positive regulation of GTPase activity. Located in cell leading edge. Orthologous to human SH3BP1 (SH3 domain binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Sh3bp1 Products (1)

mRNA Protein Name
NM_001171981.1 NP_001165452.1 SH3 domain-binding protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables GTPase activator activity IMP
IMP: Inferred from mutant phenotype
21658605 RGD
Biological Process GO Annotation Evidence References Source
involved in cell migration IMP
IMP: Inferred from mutant phenotype
21658605 RGD
involved in filopodium assembly IMP
IMP: Inferred from mutant phenotype
21658605 RGD
involved in positive regulation of GTPase activity IMP
IMP: Inferred from mutant phenotype
21658605 RGD
Cellular Component GO Annotation Evidence References Source
located in cell leading edge IDA
IDA: Inferred from direct assay
21658605 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

SH3 domain-binding protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12829 SH3BGRL3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12830 SH3BP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sh3bp1 NCBI NCBI:23616