Kdelr2 - KDEL endoplasmic reticulum protein retention receptor 2 Gene

Rattus norvegicus

Gene ID: 304290 | Gene type: protein coding

About Kdelr2

Summary

Predicted to enable KDEL sequence binding activity. Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport; protein retention in ER lumen; and retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Located in cis-Golgi network and endoplasmic reticulum. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 21. Orthologous to human KDELR2 (KDEL endoplasmic reticulum protein retention receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

Kdelr2 Products(1)

mRNA	Protein	Name
NM_001013122.2	NP_001013140.1	ER lumen protein-retaining receptor 2

Gene Ontology

Cellular Component

Cellular Component GO Annotation	Evidence	Reference	Source
located in cis-Golgi network	IDA IDA: Inferred from direct assay	19474315	RGD
located in endoplasmic reticulum	IDA IDA: Inferred from direct assay	19474315	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

ER lumen protein-retaining receptor 2

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2

KDEL receptor 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P2674	KDEL		/	Unkown
HY-RS07202	KDELR2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Kdelr2	NCBI	NCBI:11014
Mus musculus	Kdelr2	NCBI	NCBI:66913

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