2. Gene
  3. Srd5a3 - steroid 5 alpha-reductase 3 Gene

Srd5a3 - steroid 5 alpha-reductase 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as S5AR 3; RGD1308828

Gene ID: 305291 | Gene type: protein coding

About Srd5a3

Summary

Predicted to enable 3-oxo-5-alpha-steroid 4-dehydrogenase activity and oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor. Predicted to be involved in dolichol biosynthetic process; dolichol-linked oligosaccharide biosynthetic process; and polyprenol catabolic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum. Human ortholog(s) of this gene implicated in Kahrizi syndrome and congenital disorder of glycosylation Iq. Orthologous to human SRD5A3 (steroid 5 alpha-reductase 3). [provided by Alliance of Genome Resources, Apr 2022]

Srd5a3 Products(2)

mRNA Protein Name
NM_001013990.1 NP_001014012.1 polyprenol reductase isoform 1
NM_001401433.1 NP_001388362.1 polyprenol reductase isoform 2
Protein Preferred Names Protein Names

polyprenol reductase

3-oxo-5-alpha-steroid 4-dehydrogenase 3

SR type 3

probable polyprenol reductase

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS21945 Srd5a3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-163938A PROTAC erf3a Degrader-2 / Unkown
HY-RS13756 SRD5A3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Srd5a3 NCBI NCBI:79644