1. Gene
  2. Nkx3-1 - NK3 homeobox 1 Gene

Nkx3-1 - NK3 homeobox 1 Gene

Rattus norvegicus

Also known as Nkx3.1

Gene ID: 305999 | Gene type: protein coding

About Nkx3-1

Summary

Predicted to enable several functions, including MADS box domain binding activity; cysteine-type endopeptidase activator activity involved in apoptotic process; and Estrogen receptor binding activity. Predicted to be involved in several processes, including morphogenesis of a branching epithelium; positive regulation of cell communication; and regulation of gene expression. Predicted to act upstream of or within animal organ development; chordate embryonic development; and dorsal aorta development. Predicted to be located in cytosol; nucleoplasm; and site of DNA damage. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Orthologous to human NKX3-1 (NK3 homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Nkx3-1 Products(2)

mRNA Protein Name
NM_001034144.1 NP_001029316.1 homeobox protein Nkx-3.1
NM_001034144.1 NP_001029316.1 homeobox protein Nkx-3.1
Protein Preferred Names Protein Names

homeobox protein Nkx-3.1

NK-3 transcription factor, locus 1

Orthologs Information

Species Symbol Source ID
Homo sapiens Nkx3-1 NCBI NCBI:4824