CTNNA1 - Ctnna1 catenin alpha 1 Gene

Also Known as Catna1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 307505

Summary

Predicted to enable several functions, including beta-catenin binding activity; cytoskeletal protein binding activity; and gamma-catenin binding activity. Involved in several processes, including gap junction assembly; gonad development; and response to estrogen. Located in acrosomal vesicle; adherens junction; and plasma membrane. Biomarker of esophageal Cancer and lung carcinoma. Human ortholog(s) of this gene implicated in patterned macular dystrophy 2. Orthologous to human CTNNA1 (catenin alpha 1). [provided by Alliance of Genome Resources, Apr 2022]

CTNNA1 Products (1)

mRNA Protein Name
NM_001007145.1 NP_001007146.1 catenin alpha-1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables beta-catenin binding IPI
IPI: Inferred from physical interaction
12960056 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
12640114 RGD
enables protein-containing complex binding IPI
IPI: Inferred from physical interaction
8834786 RGD
Biological Process GO Annotation Evidence References Source
involved in axon regeneration IEP
IEP: Inferred from expression pattern
12387456 RGD
involved in gap junction assembly IMP
IMP: Inferred from mutant phenotype
12577316 RGD
involved in male gonad development IEP
IEP: Inferred from expression pattern
7507830 RGD
involved in odontogenesis of dentin-containing tooth IEP
IEP: Inferred from expression pattern
10681393 RGD
involved in ovarian follicle development IEP
IEP: Inferred from expression pattern
10864803 RGD
involved in response to estrogen IEP
IEP: Inferred from expression pattern
10864803 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
16678996 RGD
Cellular Component GO Annotation Evidence References Source
located in acrosomal vesicle IDA
IDA: Inferred from direct assay
16755864 RGD
located in adherens junction IDA
IDA: Inferred from direct assay
8834786 RGD
located in cell-cell junction IDA
IDA: Inferred from direct assay
15197645 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

catenin alpha-1

  • catenin (cadherin associated protein), alpha 1

  • catenin (cadherin-associated protein), alpha 1, 102kDa

  • catenin alpha-1-like

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03302 CTNNA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29453 Ctnna1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens CTNNA1 NCBI NCBI:1495