CTNNA1 - catenin alpha 1 Gene

Also Known as MDPT2; CAP102

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 1495

About CTNNA1

Cytogenetic location: 5q31.2 Genomic coordinates (GRCh38): 5:138,753,425-138,935,034 (from NCBI)

This gene has 44 transcripts (splice variants), 226 orthologues, 4 paralogues and is associated with 4 phenotypes. Ubiquitous expression in esophagus (RPKM 69.8), lung (RPKM 58.9) and 25 other tissues.

Summary

This gene encodes a member of the catenin family of proteins that play an important role in cell adhesion process by connecting Cadherins located on the plasma membrane to the actin filaments inside the cell. The encoded mechanosensing protein contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal tension, resulting in the reconfiguration of cadherin-actin filament connections. Certain mutations in this gene cause butterfly-shaped pigment dystrophy. [provided by RefSeq, May 2016]

CTNNA1 Products (37)

mRNA Protein Name
NM_001290307.3 NP_001277236.1 catenin alpha-1 isoform 2
NM_001290309.3 NP_001277238.1 catenin alpha-1 isoform 3
NM_001290310.3 NP_001277239.1 catenin alpha-1 isoform 4 precursor
NM_001290312.1 NP_001277241.1 catenin alpha-1 isoform 5
NM_001323982.2 NP_001310911.1 catenin alpha-1 isoform 1
NM_001323983.1 NP_001310912.1 catenin alpha-1 isoform 1
NM_001323984.2 NP_001310913.1 catenin alpha-1 isoform 1
NM_001323985.2 NP_001310914.1 catenin alpha-1 isoform 6
NM_001323986.2 NP_001310915.1 catenin alpha-1 isoform 7
NM_001323987.1 NP_001310916.1 catenin alpha-1 isoform 5
NM_001323988.1 NP_001310917.1 catenin alpha-1 isoform 5
NM_001323989.1 NP_001310918.1 catenin alpha-1 isoform 5
NM_001323990.1 NP_001310919.1 catenin alpha-1 isoform 5
NM_001323991.1 NP_001310920.1 catenin alpha-1 isoform 5
NM_001323992.1 NP_001310921.1 catenin alpha-1 isoform 5
NM_001323993.1 NP_001310922.1 catenin alpha-1 isoform 5
NM_001323994.1 NP_001310923.1 catenin alpha-1 isoform 5
NM_001323995.1 NP_001310924.1 catenin alpha-1 isoform 5
NM_001323996.1 NP_001310925.1 catenin alpha-1 isoform 5
NM_001323997.1 NP_001310926.1 catenin alpha-1 isoform 5
NM_001323998.1 NP_001310927.1 catenin alpha-1 isoform 5
NM_001323999.1 NP_001310928.1 catenin alpha-1 isoform 5
NM_001324000.1 NP_001310929.1 catenin alpha-1 isoform 5
NM_001324001.1 NP_001310930.1 catenin alpha-1 isoform 8
NM_001324002.1 NP_001310931.1 catenin alpha-1 isoform 9
NM_001324003.1 NP_001310932.1 catenin alpha-1 isoform 9
NM_001324004.1 NP_001310933.1 catenin alpha-1 isoform 9
NM_001324005.1 NP_001310934.1 catenin alpha-1 isoform 9
NM_001324006.1 NP_001310935.1 catenin alpha-1 isoform 10
NM_001324007.1 NP_001310936.1 catenin alpha-1 isoform 10
NM_001324008.1 NP_001310937.1 catenin alpha-1 isoform 10
NM_001324009.1 NP_001310938.1 catenin alpha-1 isoform 10
NM_001324010.1 NP_001310939.1 catenin alpha-1 isoform 10
NM_001324011.1 NP_001310940.1 catenin alpha-1 isoform 11
NM_001324012.1 NP_001310941.1 catenin alpha-1 isoform 12
NM_001324013.1 NP_001310942.1 catenin alpha-1 isoform 12
NM_001903.5 NP_001894.2 catenin alpha-1 isoform 1
Molecular Function GO Annotation Evidence References Source
enables beta-catenin binding IPI
IPI: Inferred from physical interaction
7650039 GOA
enables cadherin binding IPI
IPI: Inferred from physical interaction
7650039 GOA
enables gamma-catenin binding IPI
IPI: Inferred from physical interaction
7650039 GOA
enables identical protein binding IPI
IPI: Inferred from physical interaction
23292143 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
12477722 GOA
enables vinculin binding IPI
IPI: Inferred from physical interaction
9700171 GOA
Biological Process GO Annotation Evidence References Source
involved in cellular response to indole-3-methanol IDA
IDA: Inferred from direct assay
10868478 GOA
Cellular Component GO Annotation Evidence References Source
part of catenin complex IDA
IDA: Inferred from direct assay
7650039 GOA
located in cell-cell junction IDA
IDA: Inferred from direct assay
7650039 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CTNNA1 Protein Structure

Vinculin

Vinculin: Vinculin family (19 - 334)

Vinculin

Vinculin: Vinculin family (338 - 867)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 906 a.a.
Protein Preferred Names Protein Names

catenin alpha-1

  • alpha-E-catenin

CTNNA1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
CTNNA1 P35221 ECT2 Homo sapiens Q9H8V3 22750944
Intra
CTNNA1 P35221 VCL Homo sapiens P18206-2
GMS
23292143
Intra
CTNNA1 P35221 VCL Homo sapiens P18206-2 23292143
Cross
CTNNA1 P35221 Lima1 Mus musculus Q9ERG0-2 18093941
Intra
CTNNA1 P35221 NFKBIA Homo sapiens P25963 24509793
Intra
CTNNA1 P35221 NFKBIA Homo sapiens P25963 24509793
Intra
CTNNA1 P35221 CTNNB1 Homo sapiens P35222 17052462
Intra
CTNNA1 P35221 CTNNB1 Homo sapiens P35222 24509793
Intra
CTNNA1 P35221 CTNNB1 Homo sapiens P35222 12640114
Intra
CTNNA1 P35221 CTNNA1 Homo sapiens P35221 23292143
Intra
CTNNA1 P35221 APC Homo sapiens P25054
PLA
25241761
Intra
CTNNA1 P35221 EGFR Homo sapiens P00533
PLA
25241761
Intra
CTNNA1 P35221 CDH1 Homo sapiens P12830 22750944
Intra
CTNNA1 P35221 RACGAP1 Homo sapiens Q9H0H5 22750944
Cross: Cross-species interaction Intra: Intraspecies interaction

CTNNA1 Antibodies

Cat. No. Product Name Application Reactivity
HY-P82312 CTNNA1 Antibody (YA2057) WB, IP Human, Mouse, Rat
HY-P82312A CTNNA1 Antibody (YA2057)(PBS only) WB, IP Human, Mouse, Rat

Related Diseases

Diseases Alias
Macular Dystrophy, Patterned, 2
  • Patterned Macular Dystrophy 2

  • MDPT2

  • Macular Dystrophy, Butterfly-Shaped Pigmentary, 2

  • Butterfly-Shaped Pigmentary Maculary Dystrophy 2

Butterfly-Shaped Pigment Dystrophy
  • Butterfly-Shaped Pattern Dystrophy

  • Butterfly-Shaped Pigmentary Macular Dystrophy

Hereditary Breast Ovarian Cancer Syndrome
  • Hereditary Breast And Ovarian Cancer Syndrome

  • Brca1- And Brca2-Associated Hereditary Breast And Ovarian Cancer

  • Breast And/Or Ovarian Cancer

  • Breast And Ovarian Cancer Syndrome

  • Hboc Syndrome

  • Hereditary Breast And Ovarian Cancer

  • Brca1- Brca2-Associated Hboc

Colorectal Cancer
  • Colon Cancer

  • Colorectal Carcinoma

  • Colon Carcinoma

  • Colorectal Cancer, Susceptibility To

  • Carcinoma Of Colon

  • CRC

  • Colorectal Cancer With Chromosomal Instability, Somatic

  • Colon Cancer, Somatic

  • Colon Cancer, Susceptibility To

  • Colonic Neoplasms

  • Colorectal Neoplasms

  • Colorectal Cancer, Somatic

  • Colon Cancer, Advanced, Somatic

  • Colonic Carcinoma

  • Colorectal Carcinomas

  • Colon Cancers

  • Colorectal Cancers

  • Cancer, Colorectal, Somatic

  • Cancer, Colon

  • Cancer, Colorectal, Susceptibility To

  • Colorectal Neoplasm

  • Colonic Neoplasm

  • Malignant Tumor Of Colon

Diffuse Gastric And Lobular Breast Cancer Syndrome
  • Hereditary Diffuse Gastric Cancer

  • HDGC

  • LBC

  • Familial Diffuse Gastric Cancer

  • Fdgc

  • Hereditary Diffuse Gastric Adenocarcinoma

  • Breast Cancer, Lobular

  • Gastric Cancer, Familial Diffuse, And Cleft Lip With Or Without Cleft Palate

  • DGLBC

  • Gastric Cancer, Hereditary Diffuse

  • Gastric Cancer, Familial Diffuse Breast Cancer, Lobular

  • Diffuse Gastric And Lobular Breast Cancer Syndrome With Or Without Cleft Lip And/Or Palate

  • E-Cadherin-Associated Hereditary Gastric Cancer

  • Familial Diffuse Cancer Of Stomach

  • Hereditary Diffuse Cancer Of Stomach

  • Gastric Cancer Familial Diffuse

  • Gastric Cancer Familial Diffuse And Cleft Lip With Or Without Cleft Palate

  • Cancer, Gastric, Hereditary Diffuse

Diffuse Gastric Cancer
  • Hereditary Diffuse Gastric Adenocarcinoma

  • Hereditary Diffuse Gastric Cancer

  • Signet Cell Adenocarcinoma

  • Signet Ring Cell Carcinoma

  • Signet Ring Cell Gastric Carcinoma

  • Signet Ring Gastric Carcinoma

  • Fdgc

  • Familial Diffuse Cancer Of Stomach

  • Familial Diffuse Gastric Cancer

  • Gastric Cancer, Familial Diffuse

  • Gastric Cancer, Hereditary Diffuse

  • Hdgc

  • Hereditary Diffuse Cancer Of Stomach

  • Diffuse Gastric Cancer Syndrome

  • Cancer, Gastric, Diffuse

  • Carcinoma, Signet Ring Cell

  • Gastric Signet Ring Carcinoma

Polyposis Syndrome, Hereditary Mixed, 1
  • HMPS1

  • Colorectal Adenoma And Carcinoma 1

  • Crac1

  • Colorectal Cancer 4

  • Chromosome 15q13-Q14 Duplication Syndrome, 40-Kb

  • Colorectal Cancer, Susceptibility To, 4

  • Hereditary Mixed Polyposis Syndrome 1

  • Polyposis Syndrome, Hereditary Mixed 1

  • CRCS4

  • Susceptibility To Colorectal Cancer On Chromosome 15

  • Polyposis Syndrome, Mixed Hereditary 1

  • Adenomatous Polyps

Craniosynostosis
  • Premature Closure Of Cranial Sutures

  • Craniostenosis

  • Craniosynostosis Syndrome

  • Cso

  • Craniosynostoses

  • Congenital Ossification Of Cranial Sutures

  • Congenital Ossification Of Sutures Of Skull

  • Craniostosis

  • Imperfect Fusion Of Skull

  • Congenital Imperfect Closure Skull

  • Imperfect Closure Skull

  • Premature Closure Cranium Sutures

  • Deficiency Of Craniofacial Axis

Desmoid Tumor
  • Aggressive Fibromatosis

  • Desmoid Type Fibromatosis

  • Familial Infiltrative Fibromatosis

  • Desmoid Disorder, Hereditary

  • Fif

  • Fibromatosis, Familial Infiltrative

  • Deep Fibromatosis

  • Desmoid Fibromatosis

  • Hereditary Desmoid Disease

  • Musculoaponeurotic Fibromatosis

  • Desmoid-Type Fibromatosis

  • Fibromatosis, Aggressive

  • Desmoid Disease, Hereditary

  • Musculo-Aponeurotic Fibromatosis

Macular Dystrophy, Patterned, 1
  • Patterned Macular Dystrophy 1

  • MDPT1

  • Patterned Dystrophy Of Retinal Pigment Epithelium

  • Macular Dystrophy, Butterfly-Shaped Pigmentary

  • Butterfly Dystrophy Of Retinal Pigment Epithelium

  • Butterfly-Shaped Pigmentary Maculary Dystrophy 1

  • Dystrophy, Macular, Patterned, Type 1

Patterned Macular Dystrophy
  • Patterned Dystrophy Of Retinal Pigment Epithelium

Blepharocheilodontic Syndrome 1
  • Blepharocheilodontic Syndrome

  • Bcd Syndrome

  • Elschnig Syndrome

  • Clefting, Ectropion, And Conical Teeth

  • Lagophthalmia With Bilateral Cleft Lip And Palate

  • Blepharo-Cheilo-Odontic Syndrome

  • Bcds

  • Ectropion, Inferior, With Cleft Lip And/Or Palate

  • Blepharo-Cheilo-Dontic Syndrome

  • BCDS1

  • Ectropion Inferior Cleft Lip And Or Palate

  • Clefting-Ectropion-Conical Teeth Syndrome

  • Ectropion Inferior-Cleft Lip And/Or Palate Syndrome

  • Lagophthalmia-Cleft Lip And Palate Syndrome

  • Blepharocheilodontic Syndrome, Type 1

Gastric Cancer
  • Stomach Cancer

  • Gastric Carcinoma

  • Stomach Carcinoma

  • Gastric Cancer, Somatic

  • Gastric Neoplasm

  • Carcinoma Of Stomach

  • Stomach Neoplasms

  • Malignant Neoplasm Of Stomach

  • Gastric Cancer Risk After H. Pylori Infection

  • Cancer Of The Stomach

  • Adult Stomach Cancer

  • Adult Stomach Carcinoma

  • GASC

  • Gastric Cancer Intestinal

  • Gastric Cancers

  • Gastric Carcinomas

  • Cancer, Gastric

  • Stomach Neoplasm

  • Malignant Neoplasm Of Body Of Stomach

  • Malignant Tumor Of Lesser Curve Of Stomach

  • Gastrocarcinoma Of Unspecified Site

  • Leather Bottle Stomach

  • Carcinoma Of Fundus Of Stomach

  • Cancer Of Fundus Of Stomach

  • Primary Malignant Neoplasm Of Body Of Stomach

  • Cancer Of Body Of Stomach

  • Primary Malignant Neoplasm Of Pyloric Antrum

  • Pyloric Antrum Cancer

  • Malignant Tumour Of Stomach

Inherited Cancer-Predisposing Syndrome
  • Hereditary Cancer-Predisposing Syndrome

Bap1 Tumor Predisposition Syndrome
  • Bap1-Related Tumor Predisposition Syndrome

  • Common Syndrome

  • Bap1 Cancer Syndrome

  • Bap1-Tpds

  • Cutaneous/Ocular Melanoma, Atypical Melanocytic Proliferations, And Other Internal Neoplasms

  • Tumor Predisposition Syndrome

  • Tumor Susceptibility Linked To Germline Bap1 Mutations

  • Cutaneous/Ocular Melanoma, Atypical Melanocytic Proliferations, Other Internal Neoplasms

  • Tumor Predisposition

Bladder Cancer
  • Urinary Bladder Cancer

  • Bladder Carcinoma

  • Urinary Bladder Carcinoma

  • Bladder Neoplasm

  • Bladder Tumor

  • Cancer, Bladder

  • Malignant Neoplasm Of Urinary Bladder

  • Carcinoma Of Bladder

  • Bladder Cancer, Somatic

  • Tumor Of The Bladder

  • Carcinoma Of Urinary Bladder

  • Bladder Carcinoma Urinary

  • Cancer Of The Urinary Bladder

  • Cancer, Urinary Bladder

  • Malignant Bladder Neoplasm

  • Malignant Bladder Tumor

  • Neoplasm Of The Bladder

  • Neoplasm Of The Urinary Bladder

  • Tumor Of The Urinary Bladder

  • Urinary Bladder Neoplasm

  • BLC

  • Urothelial Carcinoma Of The Bladder

  • Bladder Tumors

  • Urinary Bladder Neoplasms

  • Bladder Cancer Nos

  • Vesical Cancer Nos

  • Malignant Neoplasm Of Bladder, Part Unspecified

  • Malignant Tumour Of Urinary Bladder

  • Primary Malignant Neoplasm Of Bladder

Arrhythmogenic Right Ventricular Cardiomyopathy
  • Arrhythmogenic Right Ventricular Dysplasia

  • Arvc

  • Arvd

  • Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy

  • Arvc Cardiomyopathy

  • Arrhythmogenic Right Ventricular Cardiomyopathy-Dysplasia

  • Arvd/C

  • Right Ventricular Dysplasia, Arrhythmogenic

  • Ventricular Dysplasia, Right, Arrhythmogenic

  • Cardiomyopathy, Ventricular, Right, Arrhythmogenic

  • Dysplasia, Arrhythmogenic Right Ventricular

Fundus Dystrophy
  • Retinal Dystrophy

  • Retinal Dystrophies

  • Dystrophy, Retinal

Endometrial Cancer
  • Endometrial Carcinoma

  • Endometrial Neoplasm

  • Malignant Neoplasm Of Endometrium

  • Endometrioid Carcinoma

  • Endometrial Neoplasms

  • Carcinoma, Endometrioid

  • Endometrial Cancer, Familial

  • Endometrial Carcinoma, Somatic

  • Endometrial Cancer, Susceptibility To

  • Endometrial Ca

  • Malignant Endometrial Neoplasm

  • Neoplasm Of Endometrium

  • Primary Malignant Neoplasm Of Endometrium

  • Tumor Of Endometrium

  • Carcinoma Of The Endometrium

  • Endometrioid Carcinoma Of Female Reproductive System

  • ENDMC

  • Carcinoma Endometrioid

  • Endometrial Cancers

  • Cancer, Endometrial

  • Uterine Corpus Cancer

Gastric Diffuse Adenocarcinoma
  • Diffuse Gastric Adenocarcinoma

  • Carcinoma, Diffuse Type

Microinvasive Gastric Cancer
  • Early Gastric Cancer

  • Surface Gastric Cancer

Linitis Plastica
  • Leather-Bottle Stomach

Esophageal Cancer
  • Esophageal Carcinoma

  • Carcinoma Of Esophagus

  • Esophageal Squamous Cell Carcinoma, Somatic

  • Esophageal Carcinoma, Somatic

  • Esophagus Cancer

  • Gastric Cardia Adenocarcinoma

  • Esophageal Neoplasms

  • Esophageal Cancer, Somatic

  • Cancer Of Esophagus

  • Cancer Of Oesophagus

  • Carcinoma Of Oesophagus

  • Ca Lower Third Oesophagus

  • Ca Middle Third Oesophagus

  • Malignant Neoplasm Of Distal Third Of Esophagus

  • Malignant Neoplasm Of Lower Third Of Oesophagus

  • Malignant Neoplasm Of Middle Third Of Oesophagus

  • Malignant Neoplasm Of Proximal Third Of Esophagus

  • Malignant Neoplasm Of Upper Third Esophagus

  • Malignant Tumor Of Abdominal Esophagus

  • Malignant Tumor Of Distal Third Of Esophagus

  • Malignant Tumor Of Proximal Third Of Esophagus

  • Malignant Tumor Of The Middle Third Of The Esophagus

  • ESCR

  • Aerodigestive Tract Cancer

  • Escc

  • Esophageal Squamous Cell Carcinoma

  • Cancer, Esophageal

  • Malignant Neoplasm Of Esophagus

  • Squamous Cell Carcinoma Of Esophagus

  • Malignant Neoplasm Of Middle Third Of Esophagus

Tubular Adenocarcinoma
  • Tubular Carcinoma

  • Adenocarcinoma Tubular

  • Adenocarcinoma, Tubular

Cholangiocarcinoma
  • Cholangiocarcinoma, Susceptibility To

  • Extrahepatic Cholangiocarcinoma

  • Intrahepatic Cholangiocarcinoma

  • Chlc

  • Chlc, Susceptibility To

  • Cc

  • Cholangiocarcinoma Of Biliary Tract

  • Cholangiocellular Carcinoma

  • Distal Cholangiocarcinoma

  • Perihilar Cholangiocarcinoma

  • Bile Duct Cancer

  • Cca

  • Adult Primary Cholangiocellular Carcinoma

  • Bile Duct Carcinoma

Testicular Cancer
  • Testis Cancer

  • Testicular Carcinoma

  • Testicular Neoplasms

  • Malignant Neoplasm Of Testis

  • Childhood Neoplasm Of The Testis

  • Neoplasm Of Testis

  • Pediatric Testicular Neoplasm

  • Testicular Tumor

  • Testis Neoplasm

  • Testicular Tumors

  • Testicular Neoplasm

  • Testicular Malignant Germ Cell Tumor

  • Childhood Testicular Neoplasm

  • Carcinoma Of The Testis

  • Cancer Of Testis

  • Malignant Neoplasm Of Testis, Nos

  • Malignant Neoplasm Of Testis, Unspecified

  • Malignant Tumour Of Testis

  • Testicle Cancer

  • Primary Malignant Neoplasm Of Testis

Ovarian Cancer
  • Ovarian Carcinoma

  • Ovarian Neoplasm

  • Malignant Tumour Of Ovary

  • Cancer Of The Ovary

  • Epithelial Ovarian Cancer

  • Neoplasm Of Ovary

  • Ovarian Neoplasms

  • Ovarian Cancers

  • Malignant Neoplasm Of Ovary

  • Primary Malignant Neoplasm Of Ovary

  • Ovarian Cancer, Somatic

  • Malignant Ovarian Tumor

  • Ovary Neoplasm

  • Primary Ovarian Cancer

  • Tumor Of The Ovary

  • Malignant Neoplasm Of The Ovary

  • Malignant Tumor Of The Ovary

  • Ovarian Malignant Tumor

  • OC

  • Ovarian Carcinomas

  • Cancer, Ovarian

  • Cancer Of Ovary

  • Ovary Cancer

  • Ca Ovary

Dilated Cardiomyopathy
  • Familial Dilated Cardiomyopathy

  • Primary Dilated Cardiomyopathy

  • Idiopathic Dilated Cardiomyopathy

  • Congestive Cardiomyopathy

  • Idiopathic Dilation Cardiomyopathy

  • Primary Familial Dilated Cardiomyopathy

  • Cardiomyopathy, Dilated

  • DCM

  • Cardiomyopathy, Familial Dilated

  • Dilated Cardiomyopathy, Familial

  • Hypokinetic Dilated Cardiomyopathy, Familial

  • Familial Idiopathic Cardiomyopathy

  • Fdc

  • Cardiomyopathy, Familial Idiopathic

  • Idiopathic Cardiomegaly

  • Dilated Congestive Cardiomyopathy

  • Chronic Dilated Cardiomyopathy

  • Ccm - [Congestive Cardiomyopathy]

  • Cocm - [Congestive Cardiomyopathy]

  • Dcm - [Dilated Cardiomyopathy]

  • Dilated-Hypokinetic Cardiomyopathy

  • Congestive Idiopathic Cardiomyopathy

  • Primary Idiopathic Dilated Cardiomyopathy

Pancreatic Cancer
  • Pancreatic Carcinoma

  • Carcinoma Of Pancreas

  • Familial Pancreatic Carcinoma

  • Pancreatic Neoplasm

  • Pancreatic Carcinoma, Familial

  • Malignant Neoplasm Of Pancreas

  • Pancreatic Acinar Carcinoma

  • Pancreatic Tumor

  • Familial Pancreatic Cancer

  • Neoplasm Of The Pancreas

  • Cancer Of The Pancreas

  • Pancreatic Carcinoma, Somatic

  • Pancreatic Cancer, Somatic

  • Ca Body Of Pancreas

  • Ca Head Of Pancreas

  • Ca Tail Of Pancreas

  • Malignant Neoplasm Of Body Of Pancreas

  • Malignant Neoplasm Of Head Of Pancreas

  • Malignant Neoplasm Of Tail Of Pancreas

  • Pancreas Neoplasm

  • Exocrine Cancer

  • Exocrine Pancreas Carcinoma

  • Hereditary Pancreatic Cancer

  • Hereditary Pancreatic Carcinoma

  • PNCA

  • Pancreatic Cancer, Susceptibility To

  • Carcinoma Of Head Of Pancreas

  • Pancreatic Neoplasms

  • Pancreatic Tumors

  • Cancer, Pancreatic

  • Cancer Of Pancreas

  • Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site

Lobular Neoplasia
  • Lobular Carcinoma In Situ

  • Lobular Carcinoma In Situ Of Breast

  • Lobular Intraepithelial Neoplasia

  • Non-Infiltrating Lobular Carcinoma

  • Noninfiltrating Lobular Carcinoma Unspecified Site

  • Noninfiltrating Lobular Carcinoma Of Breast

  • Lobular Carcinoma In Situ Unspecified Site

Juvenile Polyposis Syndrome
  • JPS

  • Juvenile Intestinal Polyposis

  • Jip

  • Pji

  • Juvenile Gastrointestinal Polyposis

  • Juvenile Polyposis

  • Polyposis, Juvenile Intestinal

  • Polyposis, Familial, Of Entire Gastrointestinal Tract

  • Polyposis Familial Of Entire Gastrointestinal Tract

  • Polyposis Juvenile Intestinal

  • Polyposis Syndrome, Juvenile

Prostate Cancer
  • Prostate Carcinoma

  • Prostate Cancer, Familial

  • Prostate Neoplasm

  • Prostate Cancer, Somatic

  • Prostate Cancer, Susceptibility To

  • Prostatic Cancer

  • Prostatic Neoplasms

  • Hereditary Prostate Cancer

  • Prostatic Neoplasm

  • Cancer Of Prostate

  • Carcinoma Of Prostate

  • Familial Prostate Cancer

  • Familial Prostate Carcinoma

  • Malignant Tumor Of Prostate

  • Malignant Neoplasm Of Prostate

  • Prostate Cancer, Familial, Susceptibility To

  • Malignant Tumor Of The Prostate

  • Ngp - New Growth Of Prostate

  • Tumor Of The Prostate

  • Prostate Cancer, Hereditary

  • Cancer Of The Prostate

  • Malignant Neoplasm Of The Prostate

  • Prostatic Carcinoma

  • PC

  • Prca

  • Cancer, Prostate

  • Malignant Prostatic Tumour

  • Malignant Tumour Of Prostate

  • Primary Prostate Cancer

  • Primary Malignant Neoplasm Of Prostate

  • Prostate Gland Cancer

Band Heterotopia
  • Subcortical Band Heterotopia

  • Double Cortex Syndrome

  • Subcortical Laminar Heterotopia

  • Double Cortex

  • Band Heterotopia Of Brain

  • BH

  • Heco

  • Heterotopic Cortex

  • Familial Band Heterotopia

  • Dc

  • Dc Syndrome

  • Heterotopia, Subcortical Band

  • Sbh

  • Sclh

  • Bhy

Renal Cell Carcinoma, Nonpapillary
  • Renal Cell Carcinoma

  • RCC

  • Nonpapillary Renal Cell Carcinoma

  • Clear Cell Renal Cell Carcinoma

  • Hypernephroma

  • Adenocarcinoma Of Kidney

  • Renal Carcinoma, Chromophobe, Somatic

  • Clear Cell Carcinoma Of Kidney

  • Clear-Cell Metastatic Renal Cell Carcinoma

  • Clear Cell Renal Carcinoma

  • Renal Cell Carcinoma, Somatic

  • Conventional Renal Cell Carcinoma

  • Conventional Renal Cell Carcinoma

  • Renal Clear Cell Carcinoma

  • Ccrcc

  • Hereditary Clear Cell Renal Cell Carcinoma

  • Carcinoma, Renal Cell

  • Renal Cell Carcinoma, Clear Cell, Somatic

  • Renal Cell Carcinoma, Clear Cell

  • Clear Cell Kidney Carcinoma

  • Clear Cell Rcc

  • Cystic-Multilocular Variant

  • Clear Cell Renal Cell Adenocarcinoma

  • Hereditary Clear Cell Renal Cell Adenocarcinoma

  • Common Renal Cell Carcinoma

  • Crcc

  • Renal Cell Carcinoma Non-Papillary

  • Carcinoma Renal Cell

  • Renal Cell Cancer

  • Carcinoma, Renal Cell, Nonpapillary

Inflammatory Bowel Disease
  • Inflammatory Bowel Diseases

  • Bowel Disease, Inflammatory

Breast Cancer
  • Breast Carcinoma

  • Male Breast Cancer

  • Breast Cancer, Familial

  • Malignant Neoplasm Of Breast

  • Breast Cancer, Susceptibility To

  • Breast Cancer, Early-Onset

  • Malignant Tumor Of Breast

  • Carcinoma Of Male Breast

  • Breast Cancer, Invasive Ductal

  • Breast Cancer, Protection Against

  • Breast Cancer, Somatic

  • Breast Cancer, Male

  • Breast Cancer, Lobular, Somatic

  • Breast Tumor

  • Mammary Cancer

  • Mammary Tumor

  • Malignant Neoplasm Of Male Breast

  • Mammary Carcinoma

  • Male Breast Carcinoma

  • Familial Cancer Of Breast

  • Invasive Ductal Breast Carcinoma

  • Breast Cancer Susceptibility

  • Breast Cancer, Male, Susceptibility To

  • Breast Cancer, Early-Onset, Susceptibility To

  • Malignant Tumor Of The Breast

  • Mammary Neoplasm

  • Primary Breast Cancer

  • Neoplasm Of Male Breast

  • Carcinoma Of Breast

  • Breast Cancer In Men

  • Familial Breast Cancer

  • Cancer Of Breast

  • BC

  • Breast Cancer Familial

  • Breast Cancer Familial Male

  • Breast Cancer, Familial Male

  • Breast Male Carcinoma

  • Breast Neoplasms

  • Breast Neoplasms, Male

  • Mammary Tumors

  • Mammary Carcinomas

  • Cancer, Breast

  • Cancer, Breast, Susceptibility

  • Invasive Breast Ductal Carcinoma

  • Breast Neoplasm

  • Susceptibility To Breast Cancer

  • Mammary Neoplasms

  • Animal Mammary Neoplasms

  • Primary Malignant Neoplasm Of Breast

  • Infiltrating Ductal Carcinoma Of Breast

  • Infiltrating Duct Carcinoma Of Unspecified Site

  • Infiltrating Ductular Carcinoma Of Unspecified Site

  • Invasive Breast Carcinoma Of No Special Type

  • Microinvasive Carcinoma Of Breast

  • Carcinoma With Apocrine Differentiation

Exudative Vitreoretinopathy
  • Familial Exudative Vitreoretinopathy

  • Fevr

  • Criswick-Schepens Syndrome

  • Exudative Vitreoretinopathy, Familial

  • Vitreoretinopathy, Exudative )

  • Exudative Vitreoretinopathy 1

Myelodysplastic Syndrome
  • Myelodysplastic Syndromes

  • Myelodysplasia

  • MDS

  • Myelodysplastic Syndrome Included

  • Myelodysplastic Syndrome, Susceptibility To, Included

  • Myelodysplastic Syndrome, Somatic

  • Myelodysplastic Syndrome, Susceptibility To

Lynch Syndrome
  • Hereditary Nonpolyposis Colon Cancer

  • Hereditary Nonpolyposis Colorectal Cancer

  • Hereditary Nonpolyposis Colorectal Carcinoma

  • Hereditary Nonpolyposis Colorectal Neoplasms

  • Familial Nonpolyposis Colon Cancer

  • Hnpcc

  • Coca 1

  • Hereditary Defective Mismatch Repair Syndrome

  • Hereditary Non-Polyposis Colon Cancer

  • Hereditary Non-Polyposis Colon Cancer Syndrome

  • Hereditary Non-Polyposis Colorectal Cancer

  • Hereditary Non-Polyposis Colorectal Cancer Syndrome

  • Hereditary Nonpolyposis Colon Cancer Syndrome

  • Hereditary Nonpolyposis Colorectal Cancer Syndrome

  • Hereditary Nonpolyposis Colorectal Neoplasm

  • Hnpcc - Hereditary Nonpolyposis Colon Cancer

  • Cancer Family Syndrome

  • Familial Nonpolyposis Colorectal Cancer

  • Colon Cancer, Familial Nonpolyposis

  • Colorectal Neoplasms, Hereditary Nonpolyposis

  • Cancer, Colorectal, Nonpolyposis, Hereditary

  • Colorectal Cancer, Hereditary Nonpolyposis, Type 1

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Mus musculus CTNNA1 MGD MGI:88274
Rattus norvegicus CTNNA1 RGD RGD:1359485
Felis catus CTNNA1 VGNC VGNC:61254
Macaca mulatta CTNNA1 VGNC VGNC:84291
Bos taurus CTNNA1 VGNC VGNC:27799
Canis familiaris CTNNA1 VGNC VGNC:51706
Others CTNNA1 NCBI