Irx3 - iroquois homeobox 3 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 307721

Summary

Predicted to enable DNA-binding transcription activator activity; DNA-binding transcription repressor activity, RNA polymerase II-specific; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including His-Purkinje system development; energy homeostasis; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within kidney development; mesoderm development; and regulation of neuron differentiation. Predicted to be located in axon; cytoplasm; and nucleus. Orthologous to human IRX3 (iroquois homeobox 3). [provided by Alliance of Genome Resources, Apr 2022]

Irx3 Products (1)

mRNA Protein Name
NM_001395133.1 NP_001382062.1 iroquois-class homeodomain protein IRX-3

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
18815185 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

iroquois-class homeodomain protein IRX-3

  • Iroquois related homeobox 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06922 IRX3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06925 IRX6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20756 Irx3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27269 Irx3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Irx3 NCBI NCBI:79191