Mdga1 - MAM domain containing glycosylphosphatidylinositol anchor 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 309659

Summary

Involved in brain development; negative regulation of synapse assembly; and spinal cord association neuron differentiation. Is anchored component of plasma membrane. Orthologous to human MDGA1 (MAM domain containing glycosylphosphatidylinositol anchor 1). [provided by Alliance of Genome Resources, Apr 2022]

Mdga1 Products (1)

mRNA Protein Name
NM_001107618.1 NP_001101088.1 MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in brain development IEP
IEP: Inferred from expression pattern
15019943 RGD
involved in negative regulation of synapse assembly IDA
IDA: Inferred from direct assay
23358245 RGD
involved in regulation of synapse maturation IDA
IDA: Inferred from direct assay
35532105 RGD
involved in regulation of synapse maturation IMP
IMP: Inferred from mutant phenotype
35532105 RGD
involved in spinal cord association neuron differentiation IEP
IEP: Inferred from expression pattern
15019943 RGD
Cellular Component GO Annotation Evidence References Source
is active in GABA-ergic synapse IDA
IDA: Inferred from direct assay
35532105 RGD
is active in GABA-ergic synapse IMP
IMP: Inferred from mutant phenotype
35532105 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
35532105 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
35532105 RGD
located in plasma membrane IDA
IDA: Inferred from direct assay
15019943 RGD
is active in postsynaptic density membrane IDA
IDA: Inferred from direct assay
35532105 RGD
is active in postsynaptic density membrane IMP
IMP: Inferred from mutant phenotype
35532105 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

MAM domain-containing glycosylphosphatidylinositol anchor protein 1

  • ig6M

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08258 MDGA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mdga1 NCBI NCBI:266727