2. Gene
  3. Xrcc4 - X-ray repair cross complementing 4 Gene

Xrcc4 - X-ray repair cross complementing 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 309995 | Gene type: protein coding

About Xrcc4

Summary

Predicted to enable FHA domain binding activity; identical protein binding activity; and protein C-terminus binding activity. Predicted to contribute to 3' overhang single-stranded DNA endodeoxyribonuclease activity. Involved in cellular response to lithium ion. Predicted to be located in chromosome, telomeric region; cytosol; and nucleoplasm. Predicted to be part of DNA Ligase IV complex; DNA-dependent protein kinase-DNA Ligase 4 complex; and ERCC4-ERCC1 complex. Predicted to be active in cytoplasm; nucleus; and site of double-strand break. Human ortholog(s) of this gene implicated in multiple myeloma. Orthologous to human XRCC4 (X-ray repair cross complementing 4). [provided by Alliance of Genome Resources, Apr 2022]

Xrcc4 Products(1)

mRNA Protein Name
NM_001006999.1 NP_001007000.1 DNA repair protein XRCC4
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to lithium ion IEP
IEP: Inferred from expression pattern
19285016 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DNA repair protein XRCC4

X-ray repair complementing defective repair in Chinese hamster cells 4

X-ray repair cross complementing protein 4

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15899 XRCC4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-118273 IPS-05002 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Xrcc4 NCBI NCBI:7518