Arfgef1 - ADP ribosylation factor guanine nucleotide exchange factor 1 Gene

Rattus norvegicus

Also known as BIG1; RGD1560793

Gene ID: 312915 | Gene type: protein coding

About Arfgef1

Summary

Predicted to enable guanyl-nucleotide exchange factor activity; Myosin binding activity; and protein kinase A regulatory subunit binding activity. Involved in neuron projection development and positive regulation of protein kinase B signaling. Located in trans-Golgi network. Orthologous to human ARFGEF1 (ADP ribosylation factor guanine nucleotide exchange factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Arfgef1 Products(1)

mRNA	Protein	Name
NM_001277056.1	NP_001263985.1	brefeldin A-inhibited guanine nucleotide-exchange protein 1

Protein Preferred Names

Protein Names

brefeldin A-inhibited guanine nucleotide-exchange protein 1

ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)

brefeldin A-inhibited GEP 1

Arfgef1 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Arfgef1	D4A631	Myo9b	Rattus norvegicus	Q63358	Anti Bait CoIP	15644318
Intra	Arfgef1	D4A631	Myo9b	Rattus norvegicus	Q63358	Y2H	15644318

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00902	ARFGEF1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Arfgef1	NCBI	NCBI:10565

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