Eya3 - EYA transcriptional coactivator and phosphatase 3 Gene

Rattus norvegicus

Gene ID: 313027 | Gene type: protein coding

About Eya3

Summary

Predicted to enable chromatin binding activity; protein tyrosine Phosphatase activity; and protein tyrosine/serine/threonine Phosphatase activity. Predicted to be involved in several processes, including histone dephosphorylation; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; and positive regulation of DNA repair. Predicted to act upstream of or within protein dephosphorylation. Located in nucleus. Orthologous to human EYA3 (EYA transcriptional coactivator and Phosphatase 3). [provided by Alliance of Genome Resources, Apr 2022]

Eya3 Products(1)

mRNA	Protein	Name
NM_001107910.1	NP_001101380.1	eyes absent homolog 3

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	10490620	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

eyes absent homolog 3

eyes absent 3 homolog

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-135774	6-Hydroxybenzbromarone	Inhibitor	99.96%	Unkown
HY-RS04613	EYA3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Eya3	NCBI	NCBI:2140

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