Nalcn - sodium leak channel, non-selective Gene

Also Known as Vgcnl1; A530023G15Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 338370

Summary

Enables cation channel activity and leak channel activity. Involved in inorganic cation transmembrane transport and regulation of resting membrane potential. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in central nervous system. Orthologous to human NALCN (sodium leak channel, non-selective). [provided by Alliance of Genome Resources, Apr 2022]

Nalcn Products (1)

mRNA Protein Name
NM_177393.4 NP_796367.3 sodium leak channel NALCN

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables leak channel activity IMP
IMP: Inferred from mutant phenotype
17448995 MGI
enables monoatomic cation channel activity IDA
IDA: Inferred from direct assay
17448995 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
19092807 MGI
Biological Process GO Annotation Evidence References Source
involved in calcium ion transmembrane transport IDA
IDA: Inferred from direct assay
17448995 MGI
involved in potassium ion transmembrane transport IDA
IDA: Inferred from direct assay
17448995 MGI
involved in regulation of resting membrane potential IMP
IMP: Inferred from mutant phenotype
17448995 MGI
involved in sodium ion transmembrane transport IDA
IDA: Inferred from direct assay
17448995 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sodium leak channel NALCN

sodium leak channel non-selective protein

  • voltage gated channel like 1

  • voltage gated channel-like protein 1

Nalcn Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Nalcn Q8BXR5 Unc80 Mus musculus Q8BLN6
Anti Bait CoIP
19092807
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09015 NALCN Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nalcn NCBI NCBI:259232