PRSS53 - serine protease 53 Gene

Homo sapiens

Also known as POL3S; UNQ308

Gene ID: 339105 | Gene type: protein coding

About PRSS53

Cytogenetic location: 16p11.2 Genomic coordinates (GRCh38): 16:31,083,437-31,088,943 (from NCBI)

This gene has 3 transcripts (splice variants), 143 orthologues and 1 paralogue. Ubiquitous expression in skin (RPKM 1.8), spleen (RPKM 1.6) and 25 other tissues.

Summary

Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]

PRSS53 Products(1)

mRNA	Protein	Name
NM_001039503.3	NP_001034592.1	serine protease 53 precursor

PRSS53 Protein Structure

Trypsin

0
100
200
300
400
500
553 a.a.

Protein Preferred Names

Protein Names

serine protease 53

EDTP308

Related Diseases

Diseases

Alias

Coumarin Resistance

Warfarin Resistance	Warfarin Sensitivity
Coumadin Sensitivity	Warfarin Response
Poor Metabolism Of Coumarin	Coumarin, Poor Metabolism Of
CMRES

Episodic Kinesigenic Dyskinesia 1

Paroxysmal Kinesigenic Choreoathetosis	Paroxysmal Kinesigenic Dyskinesia
Dystonia 10	Familial Paroxysmal Kinesigenic Dyskinesia
Episodic Kinesigenic Dyskinesia	EKD1
Pkc	Pkd
Dyt10	Familial Pkd
Paroxysmal Kinesigenic Choreathetosis	Familial Paroxysmal Dystonia
Dystonia, Familial Paroxysmal	Dyt-Prrt2
Dystonia, Type 10

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11256	PRSS53 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	PRSS53	VGNC	VGNC:33423
Mus musculus	PRSS53	MGD	MGI:2652890
Rattus norvegicus	PRSS53	RGD	RGD:1566127
Felis catus	PRSS53	VGNC	VGNC:64402
Canis familiaris	PRSS53	VGNC	VGNC:45070

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