NCCRP1 - NCCRP1, F-box associated domain containing Gene

Also Known as FBXO50; NCCRP-1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 342897

About NCCRP1

Cytogenetic location: 19q13.2 Genomic coordinates (GRCh38): 19:39,196,964-39,201,884 (from NCBI)

This gene has 1 transcript (splice variant), 166 orthologues and 5 paralogues. Biased expression in esophagus (RPKM 89.0) and skin (RPKM 44.9).

Summary

Predicted to contribute to ubiquitin protein Ligase activity. Involved in positive regulation of cell population proliferation. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

NCCRP1 Products (1)

mRNA Protein Name
NM_001001414.2 NP_001001414.1 F-box only protein 50

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Biological Process GO Annotation Evidence References Source
involved in positive regulation of cell population proliferation IDA
IDA: Inferred from direct assay
22087255 GOA
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
22087255 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NCCRP1 Protein Structure

FBA

FBA: F-box associated region (92 - 272)

  • 0
  • 100
  • 200
  • 275 a.a.
Protein Preferred Names Protein Names

F-box only protein 50

  • NCC receptor protein 1 homolog

NCCRP1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
NCCRP1 Q6ZVX7 DDI1 Homo sapiens Q8WTU0
Y2H Array
32296183
Intra
NCCRP1 Q6ZVX7 DDI1 Homo sapiens Q8WTU0
Y2H Prey Pooling
32296183
Intra
NCCRP1 Q6ZVX7 DDI1 Homo sapiens Q8WTU0
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09074 NCCRP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus NCCRP1 MGD MGI:2685009
Canis familiaris NCCRP1 VGNC VGNC:81243
Felis catus NCCRP1 VGNC VGNC:96707
Bos taurus NCCRP1 VGNC VGNC:96700
Rattus norvegicus NCCRP1 RGD RGD:1305932
Others NCCRP1 NCBI