MTX3 - metaxin 3 Gene

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 345778

About MTX3

Cytogenetic location: 5q14.1 Genomic coordinates (GRCh38): 5:79,976,716-79,991,262 (from NCBI)

This gene has 4 transcripts (splice variants), 201 orthologues and 3 paralogues. Ubiquitous expression in brain (RPKM 5.4), thyroid (RPKM 5.2) and 25 other tissues.

Summary

Predicted to be involved in mitochondrion organization. Part of MIB complex and SAM complex. [provided by Alliance of Genome Resources, Apr 2022]

MTX3 Products (3)

mRNA	Protein	Name
NM_001010891.5	NP_001010891.4	metaxin-3 isoform 2
NM_001167741.2	NP_001161213.1	metaxin-3 isoform 1
NM_001363818.2	NP_001350747.1	metaxin-3 isoform 3

MTX3 Protein Structure

Tom37

Tom37_C

GST_C_3

0
100
200
312 a.a.

Protein Preferred Names	Protein Names
metaxin-3

MTX3 Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P83516	MTX3 Antibody (YA3261)	WB	Human, Mouse, Rat
HY-P83516A	MTX3 Antibody (YA3261)(PBS only)	WB	Human, Mouse, Rat

Related Diseases

Diseases	Alias
Loeys-Dietz Syndrome 1	Furlong Syndrome Loeys-Dietz Aortic Aneurysm Syndrome LDS1 Aat5 Loeys-Dietz Syndrome Type 1 Aortic Aneurysm, Familial Thoracic 5 Familial Throacic Aortic Aneurysm 5 Loeys-Dietz Syndrome Aortic Aneurysm Syndrome, Loeys-Dietz Type Familial Thoracic Aortic Aneurysm 5 Ldas Marfanoid Disorder-Craniosynostosis Syndrome Aneurysm, Aortic, Thoracic, Familial, Type 5 Loeys-Dietz Syndrome, Type 1 Loeys-Dietz Syndrome, Type 2a
Transient Arthritis
Childhood Lymphoma	Pediatric Lymphoma
Robinow Syndrome, Autosomal Recessive 1	Robinow Syndrome, Autosomal Recessive Autosomal Recessive Robinow Syndrome Covesdem Syndrome RRS1 Costovertebral Segmentation Defect-Mesomelia Syndrome Rrs Costovertebral Segmentation Defect With Mesomelia, Formerly Covesdem Syndrome, Formerly Costovertebral Segmentation Defect With Mesomelia Robinow Syndrome Autosomal Recessive With Aplasia/Hypoplasia Of Phalanges And Metacarpals/Metatarsals Robinow Syndrome Autosomal Recessive With Brachy-Syn-Polydactyly Robinow Syndrome, Autosomal Recessive, With Aplasia/Hypoplasia Of Phalanges And Metacarpals/Metatarsals Robinow Syndrome, Autosomal Recessive, With Brachy-Syn-Polydactyly Robinow, Autosomal Recessive Syndrome, Type 1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08830	MTX3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	MTX3	VGNC	VGNC:84449
Canis familiaris	MTX3	VGNC	VGNC:53189
Mus musculus	MTX3	MGD	MGI:2686040
Rattus norvegicus	MTX3	RGD	RGD:1583002
Felis catus	MTX3	VGNC	VGNC:63663
Bos taurus	MTX3	VGNC	VGNC:55125