2. Gene
  3. Sppl3 - signal peptide peptidase like 3 Gene

Sppl3 - signal peptide peptidase like 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Sppl3-ps1; RGD1562826

Gene ID: 360822 | Gene type: protein coding

About Sppl3

Summary

Predicted to enable aspartic endopeptidase activity, intramembrane cleaving and protein homodimerization activity. Predicted to be involved in several processes, including T cell receptor signaling pathway; positive regulation of calcineurin-NFAT signaling cascade; and proteolysis. Predicted to be located in endoplasmic reticulum-Golgi intermediate compartment membrane; plasma membrane; and rough endoplasmic reticulum. Predicted to be active in Golgi-associated vesicle membrane. Predicted to be integral component of cytoplasmic side of endoplasmic reticulum membrane and integral component of lumenal side of endoplasmic reticulum membrane. Orthologous to human SPPL3 (signal peptide peptidase like 3). [provided by Alliance of Genome Resources, Apr 2022]

Sppl3 Products(2)

mRNA Protein Name
XM_003751200.4 XP_003751248.1 signal peptide peptidase-like 3 isoform X1
XM_039090190.1 XP_038946118.1 signal peptide peptidase-like 3 isoform X2
Protein Preferred Names Protein Names

signal peptide peptidase-like 3

signal peptide peptidase 3

signal peptide peptidase-like 3, pseudogene 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13707 SPPL3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sppl3 NCBI NCBI:121665