Akap7 - A-kinase anchoring protein 7 Gene

Also Known as Akap15; Akap18; AKAP-18; AKAP18d

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 361458

Summary

Enables several functions, including AMP binding activity; protein C-terminus binding activity; and protein kinase A regulatory subunit binding activity. Involved in regulation of protein kinase A signaling. Located in several cellular components, including T-tubule; apical plasma membrane; and sarcoplasmic reticulum. Part of protein-containing complex. Orthologous to human AKAP7 (A-kinase anchoring protein 7). [provided by Alliance of Genome Resources, Apr 2022]

Akap7 Products (1)

mRNA Protein Name
NM_001001801.4 NP_001001801.1 A-kinase anchor protein 7 isoforms delta and gamma

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables AMP binding IDA
IDA: Inferred from direct assay
18082768 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
14569017 RGD
enables protein domain specific binding IPI
IPI: Inferred from physical interaction
17901878 RGD
enables protein kinase A regulatory subunit binding IDA
IDA: Inferred from direct assay
15037626 RGD
Biological Process GO Annotation Evidence References Source
involved in cAMP/PKA signal transduction IMP
IMP: Inferred from mutant phenotype
17901878 RGD
Cellular Component GO Annotation Evidence References Source
located in T-tubule IDA
IDA: Inferred from direct assay
14569017 RGD
located in apical plasma membrane IDA
IDA: Inferred from direct assay
15037626 RGD
located in exocytic vesicle IDA
IDA: Inferred from direct assay
15037626 RGD
part of protein-containing complex IDA
IDA: Inferred from direct assay
17901878 RGD
located in sarcoplasmic reticulum IDA
IDA: Inferred from direct assay
17901878 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

A-kinase anchor protein 7 isoforms delta and gamma

  • A kinase (PRKA) anchor protein 7

  • A-kinase anchor protein 18

  • A-kinase anchoring protein 18 ,isoform delta

Akap7 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Akap7 Q6JP77 Pln Rattus norvegicus P61016
Anti Bait CoIP
17901878
Intra
Akap7 Q6JP77 Pln Rattus norvegicus P61016
Peptide Array
17901878
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00522 AKAP7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Akap7 NCBI NCBI:9465