Tollip - toll interacting protein Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 361677

Summary

Enables SUMO binding activity; enzyme binding activity; and interleukin-1, type I receptor binding activity. Involved in positive regulation of protein sumoylation. Located in nuclear body and perinuclear region of cytoplasm. Orthologous to human TOLLIP (toll interacting protein). [provided by Alliance of Genome Resources, Apr 2022]

Tollip Products (1)

mRNA Protein Name
NM_001109668.1 NP_001103138.1 toll-interacting protein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables SUMO binding IPI
IPI: Inferred from physical interaction
19198660 RGD
enables interleukin-1, type I receptor binding IPI
IPI: Inferred from physical interaction
19198660 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
19198660 RGD
enables ubiquitin conjugating enzyme binding IPI
IPI: Inferred from physical interaction
19198660 RGD
enables ubiquitin protein ligase binding IPI
IPI: Inferred from physical interaction
19198660 RGD
Biological Process GO Annotation Evidence References Source
involved in positive regulation of protein sumoylation IDA
IDA: Inferred from direct assay
19198660 RGD
Cellular Component GO Annotation Evidence References Source
located in nuclear body IDA
IDA: Inferred from direct assay
19198660 RGD
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
19198660 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

toll-interacting protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14875 TOLLIP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21207 Tollip Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27723 Tollip Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tollip NCBI NCBI:54472