Cracr2a - calcium release activated channel regulator 2A Gene

Also Known as Gm462; Gm1073; Efcab4b

Species: Mus musculus

Gene Type: protein coding
Gene ID: 381812

Summary

Predicted to enable GTPase activity and calcium ion binding activity. Involved in T-helper 1 cell differentiation and positive regulation of JNK cascade. Predicted to be located in Golgi membrane; plasma membrane; and vesicle. Predicted to be active in several cellular components, including Weibel-Palade body; immunological synapse; and trans-Golgi network membrane. Is expressed in several structures, including alimentary system; bladder; cerebellum; male reproductive gland or organ; and trigeminal nerve. Orthologous to human CRACR2A (calcium release activated channel regulator 2A). [provided by Alliance of Genome Resources, Apr 2022]

Cracr2a Products (2)

mRNA Protein Name
NM_001033464.4 NP_001028636.1 EF-hand calcium-binding domain-containing protein 4B isoform 2
NM_001368877.1 NP_001355806.1 EF-hand calcium-binding domain-containing protein 4B isoform 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in T-helper 1 cell differentiation IMP
IMP: Inferred from mutant phenotype
29987160 MGI
involved in positive regulation of JNK cascade IMP
IMP: Inferred from mutant phenotype
27016526 MGI
acts upstream of or within positive regulation of calcium ion transport IGI
IGI: Inferred from genetic interaction
20418871 MGI
acts upstream of positive regulation of store-operated calcium channel activity IGI
IGI: Inferred from genetic interaction
20418871 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

EF-hand calcium-binding domain-containing protein 4B

  • EF-hand calcium binding domain 4B

  • ras-related protein Rab-46

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03137 CRACR2A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cracr2a NCBI NCBI:84766