2. Gene
  3. Mir144 - microRNA 144 Gene

Mir144 - microRNA 144 Gene

  • Gene
  • Agent
  • Ortholog
Mus musculus

Also known as Mirn144; mir-144; mmu-mir-144

Gene ID: 387162 | Gene type: ncRNA

About Mir144

Summary

MicroRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted MicroRNA stem-loop. [provided by RefSeq, Sep 2009]

Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in erythrocyte differentiation IGI
IGI: Inferred from genetic interaction
30971389 MGI
involved in gene expression IGI
IGI: Inferred from genetic interaction
30971389 MGI
involved in mRNA catabolic process IGI
IGI: Inferred from genetic interaction
30971389 MGI
involved in mRNA destabilization IGI
IGI: Inferred from genetic interaction
30971389 MGI
acts upstream of or within male sex differentiation IEP
IEP: Inferred from expression pattern
23946534 MGI
acts upstream of or within response to bacterium IEP
IEP: Inferred from expression pattern
24205035 MGI
Cellular Component GO Annotation Evidence Reference Source
part of RISC complex IDA
IDA: Inferred from direct assay
20424607 MGI
part of RNAi effector complex IDA
IDA: Inferred from direct assay
30971389 MGI
part of RNAi effector complex IMP
IMP: Inferred from mutant phenotype
30971389 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Related Agents

Pre-clinical Phase
Bioactive Molecules (12)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RI00279A hsa-miR-144-3p antagomir 99.30% Unkown
HY-RI00280A hsa-miR-144-5p antagomir 96.70% Unkown
HY-R00279 hsa-miR-144-3p mimic 97.20% Unkown
HY-R02678 mmu-miR-144-5p mimic 92.48% Unkown
HY-R00279A hsa-miR-144-3p agomir 92.32% Unkown
HY-RI00280 hsa-miR-144-5p inhibitor 97.76% Unkown
HY-R00280 hsa-miR-144-5p mimic / Unkown
HY-R00280A hsa-miR-144-5p agomir / Unkown
HY-R02678A mmu-miR-144-5p agomir / Unkown
HY-RI00279 hsa-miR-144-3p inhibitor / Unkown
HY-RI02678 mmu-miR-144-5p inhibitor / Unkown
HY-RI02678A mmu-miR-144-5p antagomir / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mir144 NCBI NCBI:406936