IGLON5 - IgLON family member 5 Gene

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 402665

About IGLON5

Cytogenetic location: 19q13.41 Genomic coordinates (GRCh38): 19:51,311,644-51,330,891 (from NCBI)

This gene has 1 transcript (splice variant), 202 orthologues and 5 paralogues. Biased expression in testis (RPKM 3.7), brain (RPKM 3.6) and 6 other tissues.

Summary

Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]

IGLON5 Products (1)

mRNA	Protein	Name
NM_001101372.3	NP_001094842.1	igLON family member 5 precursor

IGLON5 Protein Structure

V-set

Ig_2

0
100
200
300
336 a.a.

Protein Preferred Names	Protein Names
igLON family member 5	Ig-like domain-containing protein ENSP00000270642

Related Diseases

Diseases	Alias
Whipple Disease	Intestinal Lipodystrophy Whipple'S Disease Intestinal Lipophagic Granulomatosis Secondary Non-Tropical Sprue Tropheryma Whippelii Infection Whipples Disease
Chorea Gravidarum
Choreatic Disease	Chorea Hereditary Chorea
Postencephalitic Parkinson Disease	Postencephalitic Parkinsonism Parkinson Disease, Postencephalitic
Kleine-Levin Hibernation Syndrome	Kleine-Levin Syndrome Familial Kleine-Levin Syndrome Kleine Levin Syndrome Familial Hibernation Syndrome Recurrent Hypersomnolence Hypersomnia-Bulimia Syndrome
Recurrent Hypersomnia	Primary Recurrent Hypersomnia Hypersomnia Recurrent Disorders Of Excessive Somnolence Hypersomnia, Recurrent
Von Economo'S Disease	Encephalitis Lethargica Von Economo Encephalitis Von Economo Disease
Central Sleep Apnea	Central Sleep Apnea Syndrome Sleep Apnea, Central Primary Central Sleep Apnea Central Sleep Apnea, Primary Central Sleep Apnoea Syndrome Csa - [Central Sleep Apnoea] Csas - [Central Sleep Apnoea Syndrome] Central Sleep Apnoea Due To Substances Including Medications
Limbic Encephalitis
Lingual-Facial-Buccal Dyskinesia	Orofacial Dyskinesia Oro-Facial Dyskinesia Dyskinesias
Autoimmune Epilepsy
Rem Sleep Behavior Disorder	Rapid Eye Movement Sleep Behavior Disorder Rem Sleep Behaviour Disorder Rapid Eye Movement Sleep Behaviour Disorder Rem - [Rapid Eye Movement] Behaviour Disorder
Autoimmune Neuropathy
Stiff-Person Syndrome	SPS Stiff-Man Syndrome Stiff Man Syndrome Stiff Person Syndrome Moersch-Woltman Syndrome Sms Stiff-Trunk Syndrome Morsch Woltman Syndrome Stiff Person Syndrome And Related Disorders Stiff Person Spectrum Disorder Classic Stiff Person Syndrome Classic Sps Focal Stiff Limb Syndrome Focal Stiff-Person Syndrome Stiff Leg Syndrome Progressive Encephalomyelitis With Rigidity
Sleep Disorder	Sleep Disorders Non-Organic Sleep Disorder
Apnea, Obstructive Sleep	Obstructive Sleep Apnea Syndrome Obstructive Sleep Apnea Sleep Apnea, Obstructive Osa Osas Sleep Apnea/Hypopnea Syndrome Sahs Upper Airway Resistance Sleep Apnea Syndrome Apnea, Obstructive Obstructive Apnea Osahs Sleep Apnea Hypopnea Syndrome Sleep Apnea Syndrome, Obstructive Sleep Apnea Obstructive Sleep Apnea Syndromes Obstructive Sleep Apnoea Syndrome Obstructive Sleep Apnoea, Adult Osa - [Obstructive Sleep Apnoea] Obstructive Sleep Apnoea, Paediatric Obstructive Sleep Apnoea Hypopnoea Syndrome Osa Syndrome Sleep Apnoea Nos [Sas] - Sleep Apnoea Syndrome Sleep Apnoea Syndrome [Osahs] - Obstructive Sleep Apnoea-Hypopnea Syndrome [Sahs] - Sleep Apnoea-Hypopnea Syndrome
Moebius Syndrome	Mobius Syndrome Moebius Sequence Oromandibular-Limb Hypogenesis Spectrum Congenital Facial Diplegia MBS Moebius Congenital Oculofacial Paralysis Absence Or Underdevelopment Of The 6th And 7th Cranial Nerves Congenital Facial Diplegia Syndrome Congenital Oculofacial Paralysis Congenital Ophthalmoplegia And Facial Paresis Moebius Spectrum Möbius Sequence Möbius Syndrome Mobius Ii Syndrome
Hyperekplexia	Hereditary Hyperekplexia Kok Disease Congenital Stiff Man Syndrome Familial Startle Disease Sthe Stiff-Baby Syndrome Hereditary Hyperexplexia Startle Disease Exaggerated Startle Reaction Hyperexplexia Hereditary Startle Disease, Familial Startle Reaction, Exaggerated Stiff-Man Syndrome, Congenital Stiff-Person Syndrome, Congenital Congenital Stiff-Man Syndrome Congenital Stiff-Person Syndrome Familial Hyperekplexia Startle Syndrome Stiff Baby Syndrome Hyperekplexia, Hereditary Stiff-Person Syndrome
La Crosse Encephalitis	California Encephalitis California Virus Encephalitis Neuroinvasive California Encephalitis Virus Infection Californian Encephalitis Encephalitis, California California Meningoencephalitis California Encephalitis Virus Infection California Encephalitis Virus Infection Neuroinvasive Disease California Meningoencephalitis Virus Disease California Serogroup Virus Neuroinvasive Disease California Viral Encephalitis Ce - [California Encephalitis] Lac - [La Crosse Encephalitis]
Mutism
Acute Disseminated Encephalomyelitis	Acute Disseminated Encephalitis Adem Ade Encephalomyelitis Acute Disseminated Encephalomyelitis, Acute Disseminated Adem - [Acute Disseminated Encephalomyelitis]
Supranuclear Palsy, Progressive, 1	Progressive Supranuclear Palsy Steele-Richardson-Olszewski Syndrome Supranuclear Palsy, Progressive Progressive Supranuclear Ophthalmoplegia Psp PSNP1 Familial Progressive Supranuclear Palsy Richardson'S Syndrome Psp Syndrome Progressive Supranuclear Palsy 1 Supranuclear Palsy Progressive Ophthalmoplegia, Supranuclear, Progressive Steele-Richardson-Olszewksi Syndrome
Autoimmune Disease Of Peripheral Nervous System
Demyelinating Polyneuropathy	Peripheral Demyelinating Neuropathy Demyelinating Peripheral Neuropathy
Movement Disease	Movement Disorders Movement Disorder

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06644	IGLON5 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	IGLON5	VGNC	VGNC:30093
Canis familiaris	IGLON5	VGNC	VGNC:41911
Mus musculus	IGLON5	MGD	MGI:2686277
Rattus norvegicus	IGLON5	RGD	RGD:1305344
Felis catus	IGLON5	VGNC	VGNC:62893