MIR23B - microRNA 23b Gene
Also Known as MIRN23B; mir-23b; miRNA23B; hsa-mir-23b
Species: Homo sapiens
About MIR23B
This gene has 1 transcript (splice variant), 142 orthologues and 1 paralogue.
Summary
MicroRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted MicroRNA stem-loop. [provided by RefSeq, Sep 2009]
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Melanoma |
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| Prostate Cancer |
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| Hepatocellular Carcinoma |
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| Leiomyoma, Uterine |
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| Ovarian Serous Carcinoma |
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| Neuroblastoma |
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| Leukemia, Acute Lymphoblastic |
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| Oral Squamous Cell Carcinoma |
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| Cervical Cancer |
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| Bladder Cancer |
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| Leukemia, Acute Myeloid |
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| Leukemia, Chronic Lymphocytic |
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| Pancreatic Cancer |
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| Glioblastoma |
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| Mature B-Cell Neoplasm |
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| Nodular Malignant Melanoma |
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| Male Reproductive Organ Cancer |
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| Male Reproductive System Disease |
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| Urinary System Disease |
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| Renal Cell Carcinoma, Nonpapillary |
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| Prostate Disease |
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| Autonomic Nervous System Neoplasm |
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| Reproductive System Disease |
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| Endocrine Gland Cancer |
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| Peripheral Nervous System Neoplasm |
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| Immune System Disease |
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| Esophageal Disease |
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| Thoracic Cancer |
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| Endocrine System Disease |
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| Bone Sarcoma |
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| Ovary Epithelial Cancer |
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| Malignant Ovarian Surface Epithelial-Stromal Neoplasm |
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| Cervix Disease |
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| Gastrointestinal System Cancer |
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| Bladder Disease |
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| Lymphatic System Cancer |
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| Gastrointestinal System Disease |
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| Lymphatic System Disease |
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| Stomach Disease |
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| Malignant Exocrine Pancreas Neoplasm |
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| Colonic Disease |
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| Kidney Cancer |
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| Lung Cancer |
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| Female Reproductive System Disease |
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| Uterine Anomalies |
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| Oral Cavity Cancer |
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| Breast Disease |
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| Large Intestine Cancer |
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| Autoimmune Disease Of Endocrine System |
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| Intestinal Disease |
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| Respiratory System Disease |
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| Connective Tissue Cancer |
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| Pancreas Disease |
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| Head And Neck Cancer |
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| Sensory System Disease |
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| Pancreatic Ductal Adenocarcinoma |
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| Arteries, Anomalies Of |
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| Spinal Disease |
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| Hematologic Cancer |
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| Inherited Metabolic Disorder |
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| Colorectal Cancer |
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| Esophageal Cancer |
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| Malignant Astrocytoma |
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| Amino Acid Metabolic Disorder |
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| Peripheral Nervous System Disease |
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| Connective Tissue Disease |
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| Nervous System Disease |
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| Eye Disease |
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| Lymphoma, Non-Hodgkin, Familial |
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| Hypertension, Essential |
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| Skin Disease |
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| Body Mass Index Quantitative Trait Locus 11 |
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| Type 2 Diabetes Mellitus |
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