MFAP2 - microfibril associated protein 2 Gene

Homo sapiens

Also known as MAGP; MAGP1; MAGP-1

Gene ID: 4237 | Gene type: protein coding

About MFAP2

Cytogenetic location: 1p36.13 Genomic coordinates (GRCh38): 1:16,974,502-16,981,583 (from NCBI)

This gene has 6 transcripts (splice variants), 173 orthologues and 1 paralogue. Broad expression in endometrium (RPKM 22.6), gall bladder (RPKM 22.5) and 16 other tissues.

Summary

Microfibrillar-associated protein 2 is a major antigen of elastin-associated microfibrils and a candidate for involvement in the etiology of inherited connective tissue diseases. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]

MFAP2 Products(4)

mRNA	Protein	Name
NM_001135247.2	NP_001128719.1	microfibrillar-associated protein 2 isoform b precursor
NM_001135248.2	NP_001128720.1	microfibrillar-associated protein 2 isoform b precursor
NM_002403.4	NP_002394.1	microfibrillar-associated protein 2 isoform a precursor
NM_017459.3	NP_059453.1	microfibrillar-associated protein 2 isoform a precursor

MFAP2 Protein Structure

MAGP

ShK

0
100
183 a.a.

Protein Preferred Names

Protein Names

microfibrillar-associated protein 2

microfibril-associated glycoprotein 1

Related Diseases

Diseases

Alias

Senile Ectropion

Involutional Ectropion

Contractural Arachnodactyly, Congenital

Congenital Contractural Arachnodactyly	Beals Syndrome
CCA	Beals-Hecht Syndrome
Distal Arthrogryposis Type 9	Arthrogryposis, Distal, Type 9
Da9	Arachnodactyly, Contractural Beals Type
Contractures, Multiple With Arachnodactyly	Ear Anomalies-Contractures-Dysplasia Of Bone With Kyphoscoliosis
Arthrogyroposis, Distal, Type 9	Distal Arthrogyropsis Type 9
Cca Syndrome	Arachnodactyly

Phacogenic Glaucoma

Weill-Marchesani Syndrome

Gemss Syndrome	Spherophakia-Brachymorphia Syndrome
Marchesani-Weill Syndrome	Wms
Congenital Mesodermal Dystrophy	Mesodermal Dysmorphodystrophy, Congenital
Spherophakia Brachymorphia Syndrome	Mesodermal Dysmorphodystrophy Congenital
Wm Syndrome	Brachydactyly-Spherophakia Syndrome
Brachymorphy With Spherophakia Syndrome	Congenital Mesodermal Dysmorphodystrophy
Marchesani Syndrome	Weill-Marchesani Syndrome, Autosomal Recessive
Weill-Marchesani Syndrome, Autosomal Dominant

Connective Tissue Disease

Connective Tissue Diseases	Connective Tissue Disorder
Abnormality Of Connective Tissue	Disorder Of Connective Tissue
Connective Tissue Disorders

Geleophysic Dysplasia

Geleophysic Dwarfism

Gphysd

Aortic Aneurysm, Familial Thoracic 1

Thoracic Aortic Aneurysm	Annuloaortic Ectasia
Familial Thoracic Aortic Aneurysm And Aortic Dissection	Familial Aortic Dissection
Familial Taad	Familial Thoracic Aortic Aneurysm
Congenital Aneurysm Of Ascending Aorta	Familial Aortic Aneurysm
Familial Thoracic Aortic Aneurysm And Dissection	Aortic Aneurysm, Thoracic
AAT1	Faa1
Aortic Dissection, Familial	Aortic Aneurysm, Familial Thoracic
Aneurysm, Thoracic Aortic	Faa
Ftaad	Taa
Taad	Cystic Medial Necrosis Of Aorta
Familial Non-Syndromic Thoracic Aortic Aneurysm And Aortic Dissection	Aortic Aneurysm Thoracic
Familial Aortic Aneurysms	Aneurysm, Aortic, Thoracic, Familial, Type 1
Aneurysm Of Thoracic Aorta	Intrathoracic Aneurysm
Thoracic Aorta Aneurysm	Thoracic Aortic Aneurysm Without Rupture
Thoracic Aneurysm	Thorax Arterial Aneurysm
Thoracic Artery Aneurysm	Thoracic Arterial Aneurysm
Thorax Aneurysm	Thorax Aortic Aneurysm
Dissection Of Thoracic Aorta

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08376	MFAP2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	MFAP2	VGNC	VGNC:74708
Felis catus	MFAP2	VGNC	VGNC:68239
Rattus norvegicus	MFAP2	RGD	RGD:1306031
Canis familiaris	MFAP2	VGNC	VGNC:43187
Bos taurus	MFAP2	VGNC	VGNC:31422
Mus musculus	MFAP2	MGD	MGI:99559

Name
Email *

	Sorry, but the email address you supplied was invalid.