2. Gene
  3. MFAP4 - microfibril associated protein 4 Gene

MFAP4 - microfibril associated protein 4 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 4239 | Gene type: protein coding

About MFAP4

Cytogenetic location: 17p11.2 Genomic coordinates (GRCh38): 17:19,383,445-19,387,190 (from NCBI)

This gene has 5 transcripts (splice variants), 574 orthologues and 25 paralogues. Broad expression in gall bladder (RPKM 378.1), lung (RPKM 320.6) and 18 other tissues.

Summary

This gene encodes a protein with similarity to a bovine microfibril-associated protein. The protein has binding specificities for both collagen and carbohydrate. It is thought to be an extracellular matrix protein which is involved in cell adhesion or intercellular interactions. The gene is located within the Smith-Magenis syndrome region. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]

MFAP4 Products(2)

mRNA Protein Name
NM_001198695.2 NP_001185624.1 microfibril-associated glycoprotein 4 isoform 1 precursor
NM_002404.3 NP_002395.1 microfibril-associated glycoprotein 4 isoform 2 precursor

MFAP4 Protein Structure

Fibrinogen_C

Fibrinogen_C: Fibrinogen beta and gamma chains, C-terminal globular domain (39 - 254)

  • 0
  • 100
  • 200
  • 255 a.a.
Protein Preferred Names Protein Names

microfibril-associated glycoprotein 4

microfibrillar associated protein 4

Recombinant MFAP4 Proteins

Cat. No. Product Name Accession Purity
HY-P70173 MFAP4 Protein, Human (HEK293, His) AAH62415.1 (V22-A255, A173V) ≥95%
HY-P77993 MFAP4 Protein, Human (HEK293, His-Flag) P55083 (V22-A255) ≥95%

Related Diseases

Diseases Alias
Smith-Magenis Syndrome

SMS

Chromosome 17p11.2 Deletion Syndrome

17p11.2 Microdeletion Syndrome

17p11.2 Monosomy

Chromosome 17p Deletion Syndrome

Del(17)

P11.2

17p- Syndrome

Deletion 17p Syndrome

Partial Monosomy 17p
Focal Chorioretinitis
Aortic Aneurysm, Familial Thoracic 1

Thoracic Aortic Aneurysm

Annuloaortic Ectasia

Familial Thoracic Aortic Aneurysm And Aortic Dissection

Familial Aortic Dissection

Familial Taad

Familial Thoracic Aortic Aneurysm

Congenital Aneurysm Of Ascending Aorta

Familial Aortic Aneurysm

Familial Thoracic Aortic Aneurysm And Dissection

Aortic Aneurysm, Thoracic

AAT1

Faa1

Aortic Dissection, Familial

Aortic Aneurysm, Familial Thoracic

Aneurysm, Thoracic Aortic

Faa

Ftaad

Taa

Taad

Cystic Medial Necrosis Of Aorta

Familial Non-Syndromic Thoracic Aortic Aneurysm And Aortic Dissection

Aortic Aneurysm Thoracic

Familial Aortic Aneurysms

Aneurysm, Aortic, Thoracic, Familial, Type 1

Aneurysm Of Thoracic Aorta

Intrathoracic Aneurysm

Thoracic Aorta Aneurysm

Thoracic Aortic Aneurysm Without Rupture

Thoracic Aneurysm

Thorax Arterial Aneurysm

Thoracic Artery Aneurysm

Thoracic Arterial Aneurysm

Thorax Aneurysm

Thorax Aortic Aneurysm

Dissection Of Thoracic Aorta
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08378 MFAP4 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta MFAP4 VGNC VGNC:74710
Bos taurus MFAP4 VGNC VGNC:31424
Felis catus MFAP4 VGNC VGNC:68241
Mus musculus MFAP4 MGD MGI:1342276
Canis familiaris MFAP4 VGNC VGNC:43190
Rattus norvegicus MFAP4 RGD RGD:1307841
Macaca fascicularis MFAP4 NCBI
Others MFAP4 NCBI