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SCGB2A1 - secretoglobin family 2A member 1 Gene

Also Known as LPHC; LPNC; MGB2; UGB3

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 4246

About SCGB2A1

Cytogenetic location: 11q12.3 Genomic coordinates (GRCh38): 11:62,208,673-62,213,943 (from NCBI)

This gene has 1 transcript (splice variant), 106 orthologues and 1 paralogue. Biased expression in endometrium (RPKM 28.0), stomach (RPKM 15.9) and 4 other tissues.

Summary

Involved in Androgen Receptor signaling pathway. Located in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

SCGB2A1 Products (1)

mRNA	Protein	Name
NM_002407.3	NP_002398.1	mammaglobin-B precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	9720917	GOA

Biological Process GO Annotation	Evidence	References	Source
involved in androgen receptor signaling pathway	IDA IDA: Inferred from direct assay	16020486	GOA

Cellular Component GO Annotation	Evidence	References	Source
located in extracellular space	IDA IDA: Inferred from direct assay	9720917	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SCGB2A1 Protein Structure

Uteroglobin

0
95 a.a.

Protein Preferred Names	Protein Names
mammaglobin-B	lacryglobin

Recombinant SCGB2A1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P77076	SCGB2A1 Protein, Human (HEK293, Fc)	O75556/NP_002398.1 (D19-N95)	≥ 95%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases	Alias
Hypotrichosis 13	HYPT13 Hypotrichosis With Woolly Hair Hypotrichosis, Type 13
Homocystinuria-Megaloblastic Anemia, Cblg Complementation Type	Methylcobalamin Deficiency, Cblg Type HMAG Methionine Synthase Deficiency Methylcobalamin Deficiency Type Cblg Homocystinuria-Megaloblastic Anemia Due To Defect In Cobalamin Metabolism, Cblg Complementation Type Homocystinuria-Megaloblastic Anemia Cblg Type Homocystinuria-Megaloblastic Anemia Due To Defect In Cobalamin Metabolism Cblg Complementation Type Methylcobalamin Deficiency Cbl G Type Homocystinuria Due To Defect In Methylation Cbl G Cblg Functional Methionine Synthase Deficiency Type Cblg Methylcobalamin Deficiency Cblg Type Arakawa Syndrome 2
Ovarian Cancer	Ovarian Carcinoma Ovarian Neoplasm Malignant Tumour Of Ovary Cancer Of The Ovary Epithelial Ovarian Cancer Neoplasm Of Ovary Ovarian Neoplasms Ovarian Cancers Malignant Neoplasm Of Ovary Primary Malignant Neoplasm Of Ovary Ovarian Cancer, Somatic Malignant Ovarian Tumor Ovary Neoplasm Primary Ovarian Cancer Tumor Of The Ovary Malignant Neoplasm Of The Ovary Malignant Tumor Of The Ovary Ovarian Malignant Tumor OC Ovarian Carcinomas Cancer, Ovarian Cancer Of Ovary Ovary Cancer Ca Ovary
Brachydactyly, Type C	Brachydactyly Type C BDC Brachydactyly Haws Type Brachydactyly, Haws Type Brachydactyly C

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12505	SCGB2A1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS23890	Scgb2a1 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	SCGB2A1	MGD	MGI:3780828
Rattus norvegicus	SCGB2A1	RGD	RGD:735031
Others	SCGB2A1	NCBI