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SCGB2A1 Protein, Human (HEK293, Fc)

Cat. No.: HY-P77076
COA Handling Instructions

The SCGB2A1 protein is a multifunctional binding entity that may interact with androgens, steroids, and the chemotherapy drug estramustine in prostate cancer treatment. Transcriptionally regulated by steroid hormones, suggesting involvement in hormone signaling pathways. SCGB2A1 Protein, Human (HEK293, Fc) is the recombinant human-derived SCGB2A1 protein, expressed by HEK293 , with C-hFc labeled tag.

For research use only. We do not sell to patients.

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Description

The SCGB2A1 protein is a multifunctional binding entity that may interact with androgens, steroids, and the chemotherapy drug estramustine in prostate cancer treatment. Transcriptionally regulated by steroid hormones, suggesting involvement in hormone signaling pathways. SCGB2A1 Protein, Human (HEK293, Fc) is the recombinant human-derived SCGB2A1 protein, expressed by HEK293 , with C-hFc labeled tag.

Background

The SCGB2A1 protein emerges as a versatile binding entity, potentially interacting with androgens, other steroids, and the chemotherapeutic agent estramustine used in prostate cancer treatment. Additionally, it may be subject to transcriptional regulation by steroid hormones, indicating a potential involvement in hormonal signaling pathways. Structurally, SCGB2A1 forms a heterodimer consisting of a lipophilin A and a lipophilin C (mammaglobin B) monomer, arranged in a head-to-head association. The diverse binding capabilities and structural arrangement suggest that SCGB2A1 may play a multifaceted role in hormonal regulation, potentially influencing cellular responses to steroids and chemotherapeutic agents in contexts such as prostate cancer. Further investigation is warranted to unravel the specific contributions of SCGB2A1 to these complex biological processes.

Species

Human

Source

HEK293

Tag

C-hFc

Accession

O75556/NP_002398.1 (D19-N95)

Gene ID
Molecular Construction
N-term
SCGB2A1 (D19-N95)
Accession # O75556/NP_002398.1
hFc
C-term
Synonyms
Mammaglobin-B; Lacryglobin; Secretoglobin family 2A member 1; LIPHC; MGB2; UGB3
Molecular Weight

Approximately 35.6 kDa.

Purity

Greater than 95% as determined by reducing SDS-PAGE

Appearance

Solution.

Formulation

Supplied as a 0.2 μm filtered solution of PBS,pH7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

N/A.

Storage & Stability

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping

Shipping with dry ice.

Documentation

SCGB2A1 Protein, Human (HEK293, Fc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
SCGB2A1 Protein, Human (HEK293, Fc)
Cat. No.:
HY-P77076
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